本文選題：非增殖型糖尿病性視網(wǎng)膜病變黃斑水腫補(bǔ)陽(yáng)還五湯　切入點(diǎn)：氪黃激光光凝術(shù)　出處：《福建中醫(yī)藥大學(xué)》2010年碩士論文　論文類型：學(xué)位論文

【摘要】： 目的：觀察氪黃激光聯(lián)合補(bǔ)陽(yáng)還五湯加減治療非增殖型糖尿病性視網(wǎng)膜病變黃斑水腫的臨床療效。 方法：對(duì)非增殖型糖尿病性視網(wǎng)膜病變黃斑水腫40例69只眼,按隨機(jī)分配到綜合治療組20例35只眼,激光治療組20例34只眼。綜合治療組應(yīng)用氪黃激光聯(lián)合中藥方劑(補(bǔ)陽(yáng)還五湯加減)治療；激光治療組單純應(yīng)用氪黃激光治療。觀察兩組患者視力、黃斑水腫、視網(wǎng)膜出血、滲出、微動(dòng)脈瘤的改善情況,比較兩組的治療效果。 結(jié)果：(1)治療三個(gè)月后綜合治療組視力提高與激光治療組比較有顯著性差異(P=0.020,P＜0.05)；(2)兩組患者治療三個(gè)月后FFA檢查顯示黃斑水腫改善情況相比較,兩組有非常顯著性差異(P=0.034,P＜0.05)；(3)兩組患者治療三個(gè)月后OCT顯示黃斑中心視網(wǎng)膜水腫厚度與治療前比較差異均具有顯著性(P=0.000,P＜0.01),兩組相比較差異具有顯著性(P=0.025,P0.05)。綜合治療組的黃斑水腫顯著減輕。(4)治療三個(gè)月后綜合治療組與激光治療組視網(wǎng)膜出血、滲出的有效率分別是88.6%、79.4%。兩組相比有顯著性差異(P=0.049,P0.05)；(5)治療三個(gè)月后綜合治療組與激光治療組微動(dòng)脈瘤消失的有效率分別是85.7%、70.6%,兩組相比有顯著性差異(P=0.045,P0.05); 結(jié)論：1.綜合治療組對(duì)非增殖型糖尿病性視網(wǎng)膜病變黃斑水腫的治療效果優(yōu)于激光治療組。2.綜合治療組在改善視功能、減輕黃斑水腫、促進(jìn)視網(wǎng)膜出血、滲出的吸收,減少微動(dòng)脈瘤方面的療效優(yōu)于激光治療組。因此,氪黃激光聯(lián)合補(bǔ)陽(yáng)還五湯加減治療非增殖型糖尿病性視網(wǎng)膜病變黃斑水腫可能是較理想的治療方法。
[Abstract]:Objective: to observe the clinical effect of krypton yellow laser combined with Buyang Huanwu decoction on macular edema of non proliferative diabetic retinopathy. Methods: forty patients (69 eyes) with macular edema of non-proliferative diabetic retinopathy were randomly assigned to 20 cases (35 eyes) in the combined treatment group. The laser treatment group was treated with krypton yellow laser combined with traditional Chinese medicine prescription (Buyang Huanwu decoction), and the laser treatment group was treated with krypton yellow laser only. The visual acuity, macular edema and retinal hemorrhage were observed in the two groups. Exudate, the improvement of microaneurysm, compare the treatment effect between the two groups. Results there was a significant difference in visual acuity between the combined treatment group and the laser treatment group after 3 months of treatment (P < 0.05). After three months of treatment, FFA examination showed that macular edema was improved in the two groups. There was a very significant difference between the two groups (P < 0.034 P < 0.05) after three months of treatment, the thickness of central macular retinal edema on OCT was significantly different from that before treatment (P < 0.01), and there was a significant difference between the two groups (P 0.025, P 0.05). After 3 months of treatment, retinal hemorrhage was significantly alleviated in the combined treatment group and laser treatment group. The effective rates of exudation were 88.6 and 79.4, respectively. There was significant difference between the two groups (P0.049 and P0.05) after three months of treatment, the effective rates of microaneurysm disappearance in the combined treatment group and the laser treatment group were 85.7 and 70.6, respectively, and there was a significant difference between the two groups. Conclusion 1. The therapeutic effect of the combined treatment group on macular edema of non-proliferative diabetic retinopathy is better than that of the laser treatment group .2.The combined treatment group can improve the visual function, alleviate the macular edema, promote the absorption of retinal hemorrhage and exudation. Therefore, krypton yellow laser combined with Buyang Huanwu decoction in the treatment of non-proliferative diabetic retinopathy macular edema may be an ideal treatment.
【學(xué)位授予單位】：福建中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2010
【分類號(hào)】：R774.5

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