本文關(guān)鍵詞： 喉癌全切術(shù) 氣管感染 肺功能 腫瘤復(fù)發(fā)　出處：《中國老年學(xué)雜志》2014年17期 　論文類型：期刊論文

【摘要】：目的研究喉癌全切手術(shù)后患者氣管感染對肺功能及腫瘤復(fù)發(fā)的影響。方法從2012年7月至2013年7月選擇在該院實(shí)施喉癌全切術(shù)的患者94例,51例行喉癌全切術(shù),43例行喉癌全切術(shù)聯(lián)合頸部淋巴結(jié)清掃術(shù),觀察術(shù)后氣管感染情況并分析氣管感染對患者肺功能及腫瘤復(fù)發(fā)的影響。結(jié)果實(shí)施喉癌全切術(shù)的患者感染率為5.88%(3/51),顯著低于實(shí)施喉癌全切術(shù)聯(lián)合頸部淋巴結(jié)清掃術(shù)的25.58%(11/43);手術(shù)時(shí)間4 h的患者感染率為2.08%(1/48),顯著低于手術(shù)時(shí)間為4~6 h的15.63%(5/32)及6 h的57.14%(8/14),且手術(shù)時(shí)間為4~6 h的感染率亦顯著低于6 h者(均P0.05)。根據(jù)Spearman法分析手術(shù)時(shí)間與氣管感染的相關(guān)性后發(fā)現(xiàn),時(shí)間越長,感染率越高,二者呈正相關(guān)聯(lián)系(r=0.884,P=0.001)。手術(shù)后發(fā)生氣管感染的14例患者1 s用力呼氣的容積(FEV)1%為67.11±4.03,顯著高于手術(shù)前的59.59±2.85;25%肺活量的最大呼氣流量(V25)為(0.71±0.42)L/s,顯著低于手術(shù)前的(1.03±0.22)L/s(均P0.05)。手術(shù)后用力肺活量(FVC)水平下降,FEV1、最大呼氣的中段流量(MMEF)及V50水平均有所上升,但均無差異(均P0.05)。發(fā)生氣管感染的一組復(fù)發(fā)率為7.14%(1/14),與未感染組的10.00%(8/80)相比無差異(P0.05)。結(jié)論喉癌全切手術(shù)后易導(dǎo)致感染和肺功能變化,患者有一定比例的腫瘤復(fù)發(fā)癥狀,應(yīng)采取措施盡可能地規(guī)避,值得臨床關(guān)注。
[Abstract]:Objective to study the effect of trachea infection on lung function and tumor recurrence in patients with laryngeal cancer after total laryngeal cancer resection. Methods from July 2012 to July 2013, 94 patients with laryngeal cancer underwent total laryngeal cancer resection and 43 patients underwent total laryngeal cancer resection. Total laryngectomy combined with neck lymph node dissection, The effect of trachea infection on lung function and tumor recurrence was analyzed. Results the infection rate of patients undergoing total laryngeal cancer resection was 5.88 / 51, which was significantly lower than that of total laryngectomy combined with neck lymph node dissection. The infection rate of the patients with 4 hours operation time was 2.08 / 48, significantly lower than that of 15.6365 / 32 and 57.14 / 14 / 14 in 4h and 6h, and the infection rate of 4h / 6h was significantly lower than that of 6h patients (all P 0.05). According to the Spearman method, the operative time and trachea were analyzed. The correlation between infection and infection was found, The longer the infection rate, the higher the infection rate. There was a positive correlation between the two factors. The FEV1% of forced expiratory volume in 14 patients with trachea infection after operation was 67.11 鹵4.03, which was significantly higher than that of 59.59 鹵2.8525% vital capacity V25 (0.71 鹵0.42L / s), which was significantly lower than that before operation (1.03 鹵0.22L / s) (all P 0.05). The level of forced vital capacity (FVC) decreased and FEV1, MMEF1 and V50 increased. But there was no difference (P 0.05). The recurrence rate of the group with trachea infection was 7.14 / 14, which was similar to that of the non-infected group (10.00 / 8 / 80). Conclusion the laryngeal carcinoma is prone to infection and pulmonary function changes after total laryngotomy, and the patients have a certain proportion of recurrence symptoms. Measures should be taken to avoid it as far as possible, and it deserves clinical attention.
【作者單位】： 濰坊市寒亭區(qū)人民醫(yī)院耳鼻咽喉頭頸外科;
【分類號】：R739.65
，

本文編號：1515947