【摘要】：目的:探討急性ST段抬高型心肌梗死(STEMI)患者血漿單體C-反應(yīng)蛋白(mCRP)水平、整體面積應(yīng)變(GAS)與冠狀動脈(冠脈)病變程度的相關(guān)性。方法:選取就診于我院心內(nèi)科的180例患者,分為STEMI組150例和對照組30例。其中STEMI組依據(jù)Gensini積分分為:輕度組(0積分≤40)、中度組(40積分80)和重度組(積分≥80)。分析血漿mCRP水平及左室射血分?jǐn)?shù)(LVEF)值、GAS值在各組間的差異,Pearson相關(guān)分析研究mCRP水平、GAS值與Gensini積分的相關(guān)性。結(jié)果:(1)STEMI組患者血漿mCRP水平顯著高于對照組(P0.05),STEMI組各亞組間差異亦有統(tǒng)計學(xué)意義(P0.05);STEMI組GAS值低于對照組(P0.05),各亞組間差異亦有統(tǒng)計學(xué)意義(P0.05)。(2)mCRP水平與Gensini積分正相關(guān)(r=0.672,P0.05),GAS值與Gensini積分呈負(fù)相關(guān)(r=-0.56,P0.05)。結(jié)論:mCRP水平、GAS與STEMI冠脈病變嚴(yán)重程度密切相關(guān),提示mCRP水平聯(lián)合GAS可以早期、無創(chuàng)評估STEMI病情嚴(yán)重程度。
[Abstract]:Aim: to investigate the relationship between plasma C-reactive protein (mCRP) level, global area strain (GAS) and severity of coronary artery lesions in patients with acute ST segment elevation myocardial infarction (STEMI). Methods: 180 patients in cardiology were divided into STEMI group (n = 150) and control group (n = 30). According to Gensini score, STEMI group was divided into mild group (0 integral 鈮，

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