舒血寧對(duì)高血壓腎功能障礙患者治療作用研究
[Abstract]:Objective: to investigate the therapeutic effect of Shuxuening on hypertensive renal dysfunction. Methods: the clinical data of patients with hypertensive renal dysfunction treated in Xiangyang Hospital affiliated to Hubei Medical College from March 2015 to August 2016 were retrospectively analyzed and divided into control group and observation group according to their treatment methods. The control group was treated with amlodipine and Atto vastatin calcium tablets, the observation group was treated with Shuxuening on this basis, both groups were treated for 2 months. The changes of blood pressure, renal function and serum inflammatory cytokines were observed before and after treatment. Results: before treatment, there was no significant difference in the mean DBP,SBP variability and DBP variability between the two groups after treatment. The above indexes in the observation group were significantly lower than those in the control group (P0.05). There was no significant difference in renal function between the two groups before treatment. After treatment, the levels of m ALB, 尾 _ 2-MG and ACR in the observation group were significantly lower than those in the control group (P0.001). There was no significant difference in serum inflammatory cytokines between the two groups before treatment. After treatment, the serum levels of D-DU IL-6 and TNF- 偽 in the observation group were significantly lower than those in the control group (P0.001). Conclusion: Shuxuening has better curative effect on patients with hypertensive renal dysfunction and can improve blood pressure and renal function better.
【作者單位】: 湖北醫(yī)藥學(xué)院附屬襄陽醫(yī)院腎內(nèi)科;
【基金】:湖北省醫(yī)學(xué)科技基金(1206ky30)
【分類號(hào)】:R544.1;R692
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