【摘要】：目的探討射頻消融術聯合氟哌噻噸美利曲辛對快速心律失�；颊叩闹委熜Ч�。方法選取快速心律失�；颊�98例,隨機分為射頻組和聯合組各49例。兩組進行射頻消融術治療,聯合組在此基礎上口服氟哌噻噸美利曲辛片,療程均為2周。分別于術前及術后2天、2周時進行漢密爾頓焦慮量表(HAMA)和漢密爾頓抑郁量表(HAMD)評分,檢測左室舒張末期內徑(LVEDD)、左室射血分數(LVEF)、每搏量(SV)、心臟指數(CI)、舒張早期最大血液流速與舒張晚期最大血液流速比值(E/A);分別于術前及術后2周時采用SCL-90量表評價生活質量;術后2周時統(tǒng)計臨床療效及不良反應。結果術后2天及2周,兩組LVEDD均較術前降低,LVEF、SV、CI、E/A均較術前升高(P均0.01);術后2周,聯合組LVEDD低于射頻組,LVEF、SV、CI、E/A均高于射頻組(P均0.01)。術后2周時兩組SCL-90量表各項目評分均較術前降低(P均0.01),且聯合組均低于射頻組(P均0.01)。術后2周時聯合組HAMA和HAMD評分均較術前及術后2天降低,且均低于射頻組同期水平(P均0.01)。術后2周時射頻組總有效率低于聯合組(P0.05);射頻組并發(fā)癥發(fā)生率為4.08%,聯合組為8.16%,組間比較P0.05。結論射頻消融術聯合氟哌噻噸美利曲辛可明顯改善快速心律失�；颊呓箲]、抑郁狀態(tài),提高其心功能和生活質量。
[Abstract]:Objective to investigate the therapeutic effect of radiofrequency ablation combined with droperazothioate melitaxine in patients with tachyarrhythmia. Methods 98 patients with tachyarrhythmia were randomly divided into radio frequency group (n = 49) and combined group (n = 49). Radiofrequency ablation was performed in both groups, and the combined group was treated with fluoperazidone metriaxine tablets for 2 weeks. Hamilton anxiety scale (HAMA) and Hamilton Depression scale (HAMD) were evaluated before and 2 days after operation. Left ventricular end-diastolic diameter (LVEDD), left ventricular ejection fraction (LVEF), (SV), cardiac index (SV), early diastolic maximum blood velocity (CI),) and late diastolic maximum blood velocity (E / A) were measured, and the quality of life (QOL) was evaluated by SCL-90 scale before and 2 weeks after operation. The clinical efficacy and adverse reactions were analyzed 2 weeks after operation. Results on the 2nd day and 2nd week after operation, the LVEDD of the two groups was lower than that of the preoperative group, and the LVEF,SV,CI,E/A of the combined group was higher than that of the preoperative group (P0.01), and the LVEDD of the combined group was lower than that of the radiofrequency group and the LVEF,SV,CI,E/A of the combined group was higher than that of the radiofrequency group 2 weeks after operation (all P 0.01). At 2 weeks after operation, the scores of SCL-90 in both groups were lower than those before operation (P0.01), and the scores in the combined group were lower than those in the radiofrequency group (P0.01). The scores of HAMA and HAMD in the combined group were lower than those before and 2 days after operation, and were lower than those in the radiofrequency group at 2 weeks after operation (P0.01). At 2 weeks after operation, the total effective rate of radiofrequency group was lower than that of the combined group (P0.05), the incidence of complications in the radiofrequency group was 4.08 and 8.16 in the combined group, and there was a comparison between the two groups (P0.05). Conclusion radiofrequency ablation combined with droperazothioate metroxine can significantly improve anxiety and depression in patients with tachyarrhythmia and improve cardiac function and quality of life of patients with tachyarrhythmia.
【作者單位】： 安徽省第二人民醫(yī)院;中國人民解放軍第88醫(yī)院;
【分類號】：R541.7

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