本文選題：高血壓 + 尿鈉　； 參考：《中國全科醫(yī)學(xué)》2017年32期

【摘要】：目的探討原發(fā)性高血壓患者24 h尿鈉、尿鉀和24 h尿鈉鉀排泄比與左心室質(zhì)量指數(shù)(LVMI)的關(guān)系。方法選取2015—2016年新疆醫(yī)科大學(xué)第一附屬醫(yī)院心血管內(nèi)科住院的原發(fā)性高血壓患者293例,留取其24 h尿標(biāo)本,檢測24 h尿鈉、尿鉀水平和24 h尿鈉鉀排泄比。依據(jù)24 h尿鈉水平將患者分為:A組(尿鈉≤100 mmol/24h),B組(100 mmol/24 h尿鈉≤200 mmol/24 h)和C組(尿鈉200 mmol/24 h)。進(jìn)行心臟超聲心動圖檢測,記錄左心室舒張末期內(nèi)徑(LVEDD)、左心室收縮末期內(nèi)徑(LVESD)、室間隔厚度(IVST)、左心室后壁厚度(LVPWT)、左心室射血分?jǐn)?shù)(LVEF)及LVMI。結(jié)果 3組患者IVST、LVPWT比較,差異均有統(tǒng)計學(xué)意義(P0.05);其中C組IVST大于A組和B組,C組LVPWT大于A組(P0.05)。Spearman相關(guān)分析結(jié)果顯示,LVMI與24 h尿鈉鉀排泄比呈正相關(guān)(rs=0.119,P0.05),與24 h尿鈉、尿鉀無直線相關(guān)性(rs=0.139、0.087,P0.05)。多元線性回歸分析結(jié)果顯示,24 h尿鈉鉀排泄比是LVMI的影響因素[β(95%CI)=1.287(0.116,2.457),P0.05],24 h尿鈉[β(95%CI)=-0.011(-0.050,0.027)]和24 h尿鉀[β(95%CI)=0.071(-0.096,0.237)]與LVMI無明顯相關(guān)性(P0.05)。結(jié)論高血壓患者24 h尿鈉鉀排泄比與LVMI相關(guān),獨立于血壓。
[Abstract]:Objective to investigate the relationship between 24 h urinary sodium, urinary potassium and 24 h urinary sodium potassium excretion ratio and left ventricular mass index (LVMI) in patients with essential hypertension. Methods 293 patients with essential hypertension in the Department of Cardiovascular Medicine of the first affiliated Hospital of Xinjiang Medical University from 2015 to 2016 were selected and their 24 h urine samples were collected. The 24 h urinary sodium, urinary potassium level and 24 h urinary natrium / potassium excretion ratio were measured. According to the 24 h urinary sodium level, the patients were divided into two groups: group A (urine sodium 鈮，

本文編號：2036744