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基于蒙特卡羅數(shù)學(xué)模型評(píng)價(jià)不同螺距冠狀動(dòng)脈CCTA受檢者輻射劑量的特點(diǎn)與驗(yàn)證

發(fā)布時(shí)間:2018-05-02 02:16

  本文選題:冠狀動(dòng)脈造影 + 雙源CT; 參考:《輻射防護(hù)》2017年02期


【摘要】:收集61例采用雙源CT Flash大螺距冠狀動(dòng)脈CCTA(Coronary Computed Tomography Angiography,CCTA)受檢者資料,按WHO亞洲人體質(zhì)量指數(shù)(BMI)標(biāo)準(zhǔn)將研究對(duì)象分為三組:正常組(12例)、超重組(41例)和肥胖組(8例),應(yīng)用蒙特卡羅(Monte Carlo)數(shù)學(xué)模型軟件計(jì)算三組受檢者大螺距與常規(guī)螺距行CCTA的器官劑量,比較兩種螺距CCTA時(shí)受檢者的器官劑量分布特點(diǎn)及兩種螺距CCTA的有效劑量變化幅度,并與大螺距模式下CT設(shè)備直接讀取法所得有效劑量值進(jìn)行比較。結(jié)果表明,用蒙特卡羅軟件計(jì)算的雙源CT大螺距CCTA受檢者的器官劑量比常規(guī)螺距技術(shù)的劑量降低約70%,其中心臟、胸腺的器官劑量下降最為明顯,降幅最大約80%;三組CCTA受檢者大螺距較常規(guī)螺距的有效劑量(E)均降低明顯(p0.05),正常組使用大螺距技術(shù)后有效劑量E降幅最為明顯;大螺距模式下數(shù)學(xué)模型軟件模擬有效劑量E與CT設(shè)備所測(cè)有效劑量E間的偏差度小于50%。說明Monte Carlo數(shù)學(xué)模型軟件可用于檢查前預(yù)估或回顧性分析CCTA掃描時(shí)受檢者的器官劑量與有效劑量的分布情況,并預(yù)判CCTA大螺距模式對(duì)受檢者的胸部器官劑量和有效劑量,從而達(dá)到了降低輻射劑量的目的,尤其對(duì)BMI較小的受檢者(如兒童)控制輻射風(fēng)險(xiǎn)更具意義。對(duì)開展低劑量CT技術(shù)具有一定實(shí)際意義。
[Abstract]:The data of 61 cases of CCTA(Coronary Computed Tomography AngiographyContra (CCTA) with double source CT Flash large pitch coronary artery were collected. According to WHO Asian body mass index (BMI) standard, the subjects were divided into three groups: normal group (n = 12), hyperrecombination group (n = 41) and obese group (n = 8). Monte Carlo Monte Carlo (Monte Carlo Monte Carlo) model software was used to calculate the large pitch and conventional snail in three groups. The organ dose of CCTA, The organ dose distribution characteristics of the two pitch CCTA patients and the effective dose range of the two pitch CCTA were compared and compared with the effective dose values obtained by the direct reading method of CT equipment in the large pitch mode. The results showed that the organ dose of dual-source CT large pitch CCTA patients calculated by Monte Carlo software was about 70 times lower than that of conventional spiral pitch technique, in which the organ dose of heart and thymus was the most obvious. The large pitch (E) of the three groups of CCTA patients was significantly lower than that of the conventional pitch (P 0.05), and the decrease of the effective dose E was the most obvious after the use of the large pitch technique in the normal group. The deviation between effective dose E and effective dose E measured by CT equipment is less than 50 in large pitch mode. The results showed that Monte Carlo mathematical model software could be used to predict or retrospectively analyze the distribution of organ dose and effective dose during CCTA scanning, and to predict the dose and effective dose of chest organ by CCTA large pitch mode. Therefore, the aim of reducing radiation dose is achieved, especially for the lower BMI subjects (such as children) to control the radiation risk. It has certain practical significance for developing low dose CT technique.
【作者單位】: 重慶醫(yī)科大學(xué)附屬第一醫(yī)院放射科;
【基金】:國(guó)家臨床重點(diǎn)?平ㄔO(shè)項(xiàng)目基金(國(guó)衛(wèi)辦[2013]544號(hào)) 重慶市衛(wèi)生局科研基金(10-2-055)
【分類號(hào)】:R816.2

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