ABO血型與急性非ST段抬高型心肌梗死的相關(guān)性分析
發(fā)布時(shí)間:2018-04-29 15:52
本文選題:ABO血型系統(tǒng) + 心肌梗死。 參考:《中國(guó)循環(huán)雜志》2017年10期
【摘要】:目的:探討中國(guó)人群中ABO血型與急性非ST段抬高型心肌梗死(NSTEMI)的相關(guān)性。方法:回顧性分析北京安貞醫(yī)院2013-01至2014-12收治入院的1 039例NSTEMI患者(病例組)和經(jīng)冠狀動(dòng)脈(冠脈)造影證實(shí)冠脈正常的1 039例患者(對(duì)照組)的ABO血型的臨床資料。觀察記錄研究對(duì)象的臨床資料,包括年齡既往病史及ABO血型等。采用Logistic回歸模型進(jìn)行單因素及多因素分析。結(jié)果 :在病例組和對(duì)照組中:A血型287例(27.6%)和259例(24.9%),B血型345例(33.3%)和356例(34.3%)AB血型102例(9.8%)和114例(11.0%),O血型305例(29.4%)和310例(29.8%),兩組ABO血型分布差異無(wú)統(tǒng)計(jì)學(xué)意義。按A血型與非A血型、B血型與非B血型、AB血型與非AB血型和O血型與非O血型分析,在兩組間分布差異均無(wú)統(tǒng)計(jì)學(xué)意義(P0.05)。經(jīng)多因素Logistic回歸分析,在調(diào)整年齡、性別、高血壓病、糖尿病、高脂血癥腦血管疾病和吸煙等心肌梗死危險(xiǎn)因素后,模型顯示A、B及AB血型者罹患NSTEMI的風(fēng)險(xiǎn)與O血型者相似;A、B AB及O血型與NSTEMI的發(fā)生均沒有相關(guān)性。結(jié)論:ABO血型與NSTEMI的發(fā)生無(wú)關(guān)。
[Abstract]:Objective: to investigate the correlation between ABO blood group and acute non-St segment elevation myocardial infarction (NSTEMI) in Chinese population. Methods: the clinical data of 1 039 patients with NSTEMI (case group) and 1 039 patients (control group) with normal coronary artery confirmed by coronary angiography from January 2013 to December 2014-12 in Beijing Anzhen Hospital were retrospectively analyzed. To observe and record the clinical data of the subjects, including age history and ABO blood group. Single factor and multi-factor analysis were carried out by Logistic regression model. Results: in the case group and control group, 287 cases (27.6B), 259 cases (24.9%) and 33.3% (345 cases) and 356 cases (34.4%), and 114 cases (11.0g) 305 cases (29.4) and 310 cases (29.8B), there was no significant difference in the distribution of ABO blood groups between the two groups. According to the analysis of A blood group and non A blood group, B blood group and non B blood group, AB blood group and non AB blood group and O blood group and non O blood group, there was no significant difference in distribution between the two groups (P 0.05). After adjusting for age, sex, hypertension, diabetes, hyperlipidemia, cerebrovascular disease and smoking, the risk factors for myocardial infarction were analyzed by multivariate Logistic regression analysis. The model showed that the risk of NSTEMI was similar to that of O blood group. There was no correlation between NSTEMI and NSTEMI. Conclusion there is no correlation between the blood type of NSTEMI and the blood group of: ABO.
【作者單位】: 平羅縣人民醫(yī)院心內(nèi)科;首都醫(yī)科大學(xué)附屬北京安貞醫(yī)院心內(nèi)科;
【分類號(hào)】:R542.22
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