本文選題：基層醫(yī)院 + 臨床藥師　； 參考：《中國(guó)醫(yī)院藥學(xué)雜志》2017年03期

【摘要】：目的:探討基層醫(yī)院臨床藥師指導(dǎo)華法林抗凝治療非瓣膜病房顫與傳統(tǒng)治療的差異,為基層醫(yī)院臨床藥師開展臨床藥學(xué)服務(wù)提供參考。方法:2010年1月-2014年12月,收治非瓣膜病心房顫動(dòng)患者58例,隨機(jī)數(shù)字表法分成臨床藥師指導(dǎo)華法林抗凝治療組28例(指導(dǎo)組)和非臨床藥師指導(dǎo)華法林抗凝治療組30例(傳統(tǒng)組)。指導(dǎo)組由臨床藥師采用藥學(xué)服務(wù)模式指導(dǎo)患者華法林抗凝治療、INR自主監(jiān)測(cè)與劑量調(diào)整;傳統(tǒng)組由醫(yī)師依據(jù)INR值調(diào)整用藥劑量、交代藥物用法用量和注意事項(xiàng)的臨床常規(guī)方式進(jìn)行華法林抗凝治療;2組目標(biāo)國(guó)際標(biāo)準(zhǔn)化值(INR)均為2.0~3.0(年齡≥75歲者為1.5~2.5),治療開始后每間隔5 d在院監(jiān)測(cè)一次INR值。2組患者開始華法林抗凝治療的第12個(gè)月做一次隨訪調(diào)查。結(jié)果:2組患者達(dá)目標(biāo)國(guó)際標(biāo)準(zhǔn)化值(INR)的比例有顯著性差異(P0.05);自我監(jiān)測(cè)與劑量調(diào)整能力、用藥依從性和安全性方面的隨訪調(diào)查,結(jié)果有顯著性差異(P0.05)。結(jié)論:臨床藥師采用藥學(xué)服務(wù)模式指導(dǎo)華法林抗凝治療非瓣膜病心房顫動(dòng)患者的方法效果顯著。
[Abstract]:Objective: to explore the difference between warfarin anticoagulant therapy and traditional treatment in primary hospital clinical pharmacists, and to provide reference for clinical pharmacists to carry out clinical pharmaceutical care.Methods: from January 2010 to December 2014, 58 patients with non-valvular atrial fibrillation were treated.The method of random number table was divided into 28 cases of warfarin anticoagulant therapy group guided by clinical pharmacists and 30 cases of warfarin anticoagulant therapy group (traditional group) guided by non-clinical pharmacists.The guiding group was guided by pharmacists to guide the patients with warfarin anticoagulant therapy with independent monitoring and dose adjustment, while in the traditional group, the dosage was adjusted by physicians according to the value of INR.The standard value of Warfarin anticoagulant therapy in the two groups was 2.0 / 3.0 (1.5 / 2.5 for those aged 鈮，

本文編號(hào)：1753625