CT對心外膜脂肪體積與升主動脈彈性的相關(guān)性
本文選題:冠心病 + 體層攝影術(shù); 參考:《中國醫(yī)學(xué)影像學(xué)雜志》2017年07期
【摘要】:目的運用CT測量結(jié)果探討心外膜脂肪體積與升主動脈彈性的相關(guān)性,借以通過心外膜脂肪(EAT)體積早期評估升主動脈病變。資料與方法收集2016年1-9月在錦州醫(yī)科大學(xué)附屬第一醫(yī)院行冠狀動脈CT血管造影和冠狀動脈造影檢查的疑似冠心病患者169例,并根據(jù)有無冠狀動脈硬化分為對照組(60例)和研究組(109例)。研究組按冠狀動脈粥樣硬化程度評分分為輕微組、輕度組、中度組和重度組。以文獻記載EAT體積的閾值107.2 cm~3為界分為暴露組,其余為非暴露組。測量并計算EAT體積及升主動脈彈性值。分析EAT體積與升主動脈彈性值的相關(guān)性以及EAT體積與冠狀動脈粥樣硬化關(guān)系。結(jié)果對照組EAT體積與升主動脈彈性值無相關(guān)性(r=-0.156,P0.05);輕微、輕度、中度、重度組EAT體積與升主動脈彈性值間均呈負相關(guān)(r=-0.378、-0.340、-0.514、-0.459,P0.05);EAT體積是升主動脈彈性值的獨立影響因子(β=-0.009,t=-2.653,P0.05);暴露組發(fā)生冠心病的風(fēng)險是非暴露組的9.318倍。結(jié)論冠心病患者的EAT體積與升主動脈彈性有明顯的相關(guān)性。EAT體積的評價能為臨床早期預(yù)測冠心病患者升主動脈病變的發(fā)生提供有效參考。
[Abstract]:Objective to investigate the correlation between epicardial fat volume and ascending aortic elasticity by CT measurement, so as to evaluate ascending aortic lesions early by epicardial fat volume.Materials and methods 169 patients with suspected coronary artery disease who underwent coronary angiography and coronary angiography in the first affiliated Hospital of Jinzhou Medical University from January to September 2016 were collected.The patients were divided into control group (n = 60) and study group (n = 109) according to coronary artery sclerosis.The study group was divided into mild group, mild group, moderate group and severe group according to coronary atherosclerosis score.The threshold of EAT volume of 107.2 cm~3 was divided into exposure group and non-exposed group.The volume of EAT and the elastic value of ascending aorta were measured and calculated.The correlation between EAT volume and ascending aortic elasticity and the relationship between EAT volume and coronary atherosclerosis were analyzed.Results there was no correlation between the volume of EAT and the elasticity of ascending aorta in the control group.There was a negative correlation between the volume of EAT and the elastic value of ascending aorta in severe group. The volume of EAT was an independent factor of ascending aortic elasticity (尾 -0.009) and the risk of coronary heart disease in exposure group was 9.318 times of that in non-exposed group.Conclusion there is a significant correlation between the volume of EAT and the elasticity of ascending aorta in patients with coronary heart disease. The evaluation of ear volume can provide an effective reference for early clinical prediction of ascending aortic disease in patients with coronary heart disease.
【作者單位】: 錦州醫(yī)科大學(xué)附屬第一醫(yī)院放射科;唐山市人民醫(yī)院放射科;
【分類號】:R541.4;R816.2
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