本文選題：心搏驟停　切入點(diǎn)：低溫治療　出處：《中國(guó)老年學(xué)雜志》2017年17期

【摘要】：目的評(píng)估心臟驟停患者接受亞低溫治療較常溫治療是否降低死亡率和改善神經(jīng)功能預(yù)后。方法網(wǎng)絡(luò)檢索Pubmed,EMBASE and Cochrane圖書館等相關(guān)數(shù)據(jù)庫(kù),檢索2016年10月以前發(fā)表的英文隨機(jī)對(duì)照臨床試驗(yàn)(RCTs),比較心臟驟�；颊呓邮軄喌蜏刂委�(MTH)與常溫治療患者死亡率和神經(jīng)功能改善的終點(diǎn)指標(biāo)。結(jié)果總共從1 735篇文章中最終篩選了10篇RCTs,MTH較對(duì)照常溫組可顯著減少患者的死亡率(RR=0.92;95%CI,0.86~0.99;P=0.03,I2=17%),然而對(duì)神經(jīng)功能改善并無(wú)明顯差異(RR=1.22;95%CI,0.98~1.53;P=0.08,I2=53%)。結(jié)論心臟驟�；颊呓邮軄喌蜏刂委熢跍p少死亡率方面優(yōu)于常溫治療,然而需要更多的大型RCTs闡明其在神經(jīng)功能改善方面的保護(hù)作用。
[Abstract]:Objective to evaluate whether mild hypothermia therapy can reduce mortality and improve nerve function prognosis in patients with cardiac arrest. Methods relevant databases such as Pubmedmedus Embus and Cochrane library were searched online. Objective: to retrieve RCTsN published before October 2016 in a randomized controlled clinical trial to compare the mortality and neurological improvement in patients with cardiac arrest treated with mild hypothermia (MTH) and normothermia. Results A total of 1,735 articles were published in this paper. In the chapter, 10 RCTs MTH were selected, which could significantly reduce the mortality rate of patients compared with the normal temperature group. Conclusion the mortality rate of patients with cardiac arrest treated with mild hypothermia is better than that of normothermic therapy. However, there is no significant difference in the improvement of neurologic function between the two groups. Conclusion the patients with cardiac arrest received mild hypothermia therapy is superior to normal temperature therapy in reducing mortality, but there is no significant difference in the improvement of neurologic function of RCTsN MTH. Conclusion the patients with cardiac arrest received mild hypothermia therapy is superior to normal temperature therapy in reducing the mortality of the patients with cardiac arrest, but there is no significant difference in the improvement of neurologic function. However, more large RCTs are needed to elucidate its protective role in improving neurological function.
【作者單位】： 鄭州人民醫(yī)院;
【分類號(hào)】：R541.78

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