本文選題：炎癥　切入點(diǎn)：血管成形術(shù)　出處：《中國循環(huán)雜志》2017年09期 　論文類型：期刊論文

【摘要】：目的:探討中性粒細(xì)胞和淋巴細(xì)胞比值(NLR)與經(jīng)皮冠狀動(dòng)脈介入治療(PCI)后對比劑對腎功能損害的關(guān)系。方法:入選我院2015-05至2016-12期間行PCI的患者176例,入院24 h內(nèi)采血檢測白細(xì)胞計(jì)數(shù)、中性粒細(xì)胞計(jì)數(shù)、淋巴細(xì)胞計(jì)數(shù)、血肌酐(SCr)、尿素氮(BUN)、尿酸(UA)、胱抑素C(CysC)等指標(biāo),并計(jì)算NLR。按NLR水平用三分位分組法將患者分為三組:低值組(NLR1.60,n=58)、中值組(1.60≤NLR≤2.36,n=62)及高值組(NLR2.36,n=56)。分別在PCI后48 h和72 h復(fù)查SCr及CysC,用Pearson相關(guān)分析探討相關(guān)性,采用Logistic多因素回歸分析判定NLR是否是對比劑腎病(CIN)的危險(xiǎn)因素。結(jié)果:低值組、中值組和高值組的SCr及CycC水平較基線水平升高的絕對值的差異有統(tǒng)計(jì)學(xué)意義(P均0.05)。Pearson相關(guān)分析顯示,NLR與SCr及CysC升高均呈正相關(guān)(r分別為0.785、0.764,P均0.05),Logistic回歸分析顯示NLR是CIN的獨(dú)立危險(xiǎn)因素(OR=4.152,95%CI:1.145~4.106)。結(jié)論 :NLR與對比劑腎功能損傷呈正相關(guān),是CIN的獨(dú)立危險(xiǎn)因素。
[Abstract]:Objective: to investigate the relationship between neutrophil / lymphocyte ratio (NLR) and renal function damage after percutaneous coronary intervention (PCI). WBC count, neutrophil count, lymphocyte count, serum creatinine (SCR), urea nitrogen bun (BUNA), uric acid (UAA), cystatin (cystatin) CysC were measured within 24 hours after admission. The patients were divided into three groups according to the level of NLR. The patients were divided into three groups according to the level of NLR: low value group, low value group, low value group, 1.60 鈮，

本文編號：1650188