發(fā)布時(shí)間：2018-02-03 16:34

  本文關(guān)鍵詞： 原發(fā)性高血壓 踝臂動(dòng)脈脈搏波傳導(dǎo)速度 中心動(dòng)脈壓 頸動(dòng)脈內(nèi)膜中層厚度　出處：《新疆醫(yī)科大學(xué)》2015年碩士論文　論文類型：學(xué)位論文

【摘要】：目的：探討原發(fā)性高血壓患者踝臂動(dòng)脈脈搏波傳導(dǎo)速度與中心動(dòng)脈壓及頸動(dòng)脈內(nèi)膜中層厚度的相關(guān)性。方法：對(duì)2010年1月—2014年3月在新疆醫(yī)科大學(xué)第一附屬醫(yī)院高血壓科住院治療的444例原發(fā)性高血壓患者進(jìn)行回顧性研究,入選對(duì)象年齡(56.63±8.86)歲。對(duì)所有患者進(jìn)行頸動(dòng)脈內(nèi)膜中層厚度(IMT),踝臂動(dòng)脈脈搏波傳導(dǎo)速度(baPWV),中心動(dòng)脈壓(CAP)的測(cè)定。根據(jù)踝臂動(dòng)脈脈搏波傳導(dǎo)速度(baPWV)分為異常組(baPWV≥14m/s, n=208)和正常組(baPWV14m/s, n=236)。用Pearson簡(jiǎn)單相關(guān)分析高血壓患者baPWV與CAP及IMT的相關(guān)性。采用Logistic回歸分析baPWV與CAP及IMT的關(guān)系。結(jié)果：baPWV異常組的年齡、24hSBP、dSBP、nSBP、CASP、 CADP、CAPP、AP、AIx、AIx75、IMT均要高于正常組,差異有統(tǒng)計(jì)學(xué)意義(P0.05)。Pearson相關(guān)分析顯示baPWV與年齡、24hSBP、dSBP、nSBP、CASP、CAPP、 AP、AIx、AIx75、IMT相關(guān)(r值分別為0.385,0.384,0.373,0.279,0.609,0.364,0.569,0.394,0.138,0274,0.513,均P0.05),進(jìn)一步控制年齡、24hSBP、dSBP、nSBP后,CASP、CADP、CAPP、AP、AIx75、IMT仍與baPWV相關(guān)。Logistic回歸分析顯示CASP、CAPP、IMT與baPWV相關(guān)(OR值分別為1.065,1.099,29.467,均P0.05)。結(jié)論：CASP、CAPP、IMT是原發(fā)性高血壓患者baPWV增加的危險(xiǎn)因素。
[Abstract]:Objective: to investigate the correlation between pulse wave velocity of ankle brachial artery and central arterial pressure and intima-media thickness of carotid artery in patients with essential hypertension. A retrospective study was conducted on 444 patients with essential hypertension who were hospitalized in the Department of Hypertension of the first affiliated Hospital of Xinjiang Medical University from January 2010 to March 2014. The subjects were aged 56.63 鹵8.86 years. The carotid intima-media thickness (IMT) and ankle brachial artery pulse wave velocity (AVV) were measured. The measurement of central arterial pressure (CAP). According to the pulse wave velocity of ankle brachial artery (BAPWV), the patients were divided into abnormal group with PWV 鈮，

本文編號(hào)：1487847