Immune reactivity and chronic low-grade inflammation（metaflammation） play an important role in the pathogenesis of obesity-associated metabolic disorders, including type 2 diabetes and nonalcoholic fatty liver disease（NAFLD）, a spectrum of diseases that include liver steatosis, nonalcoholic steatohepatitis（NASH）, fibrosis, and cirrhosis. Increased adiposity and insulin resistance contribute to the progression from hepatic steatosis to NASH and fibrosis through the development of proinflammatory ... 

【文章來源】：World Journal of Gastroenterology. 2016,22(44)

【文章頁數(shù)】：12 頁

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