發(fā)布時(shí)間：2019-03-13 21:15

【摘要】：目的統(tǒng)計(jì)分析綿陽地區(qū)獻(xiàn)血人群2008年1月-2010年12月HBV的流行率、新發(fā)率,評(píng)估HBV在該地區(qū)的流行情況。方法收集2008年1月-2010年12月100 429人次獻(xiàn)血者人口統(tǒng)計(jì)學(xué)資料、2輪第3代ELISA試劑初篩和確證數(shù)據(jù)。分別計(jì)算初次獻(xiàn)血者和重復(fù)獻(xiàn)血者的HBV流行率,利用文獻(xiàn)報(bào)道的新發(fā)率評(píng)估模型,評(píng)估重復(fù)獻(xiàn)血人群的新發(fā)率。結(jié)果 2008年1月-2010年12月綿陽地區(qū)初次獻(xiàn)血和重復(fù)獻(xiàn)血人群的HBV流行率依次為0.97%和0.04%,重復(fù)獻(xiàn)血人群中的HBV感染新發(fā)率為0.32%。結(jié)論綿陽地區(qū)獻(xiàn)血人群具有較高的流行率和新發(fā)率,可能引起較高的HBV輸血?dú)堄囡L(fēng)險(xiǎn),應(yīng)考慮采用第4代ELISA初篩試劑和核酸檢測(cè)(NAT)降低該地區(qū)的HBV對(duì)血液安全的影響。
[Abstract]:Objective to analyze the prevalence and new incidence of HBV among blood donors in Mianyang from January 2008 to December 2010 and to evaluate the prevalence of HBV in this area. Methods the demographic data of 100 429 blood donors from January 2008 to December 2010 were collected. The data were screened and confirmed by the third generation ELISA reagent in two rounds. The prevalence of HBV in first-time blood donors and repeated blood donors were calculated, and the new rates were evaluated by using the new rate assessment model reported in the literature. Results from January 2008 to December 2010, the prevalence of HBV in the first and repeated blood donors in Mianyang was 0.97% and 0.04%, respectively. The new rate of HBV infection was 0.32% in the repeated blood donors. Conclusion Blood donors in Mianyang area have a high prevalence rate and a new rate, which may lead to a higher residual risk of HBV transfusion. The fourth generation of ELISA screening reagent and nucleic acid detection (NAT) should be considered to reduce the effect of HBV on blood safety in this area.
【作者單位】： 綿陽市紅十字中心血站;中國醫(yī)學(xué)科學(xué)院北京協(xié)和醫(yī)學(xué)院輸血研究所;
【分類號(hào)】：R512.62

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