【摘要】：目的分析急性膽囊炎患者發(fā)生醫(yī)院感染的病原菌分布及危險(xiǎn)因素,為急性膽囊炎患者醫(yī)院感染的預(yù)防控制提供參考依據(jù)。方法選取2014年1月-2016年6月醫(yī)院收治的410例急性膽囊炎患者為研究對象,統(tǒng)計(jì)醫(yī)院感染率及病原菌分布,比較不同性別、年齡、基礎(chǔ)疾病、介入性治療及膽囊結(jié)石患者的醫(yī)院感染率,采用logistic回歸分析上述因素與急性膽囊炎患者醫(yī)院感染的關(guān)系。結(jié)果 410例急性膽囊炎患者醫(yī)院感染23例,醫(yī)院感染率為5.61%,23例感染患者的送檢標(biāo)本中共分離出病原菌31株,其中革蘭陰性菌21株占67.74%,革蘭陽性菌8株占25.81%,真菌2株占6.45%,單因素分析結(jié)果顯示,性別、年齡、基礎(chǔ)疾病、介入性治療及膽囊結(jié)石與急性膽囊炎患者醫(yī)院感染的發(fā)生具有相關(guān)性(P0.05);多因素logistic回歸分析結(jié)果顯示,性別、年齡、基礎(chǔ)疾病、介入性治療及膽囊結(jié)石是急性膽囊炎患者發(fā)生醫(yī)院感染的獨(dú)立危險(xiǎn)因素。結(jié)論革蘭陰性菌是急性膽囊炎患者醫(yī)院感染的主要病原菌,且性別、年齡、基礎(chǔ)疾病、介入性治療及膽囊結(jié)石情況均是導(dǎo)致醫(yī)院感染的危險(xiǎn)因素,臨床應(yīng)根據(jù)上述情況進(jìn)行針對性干預(yù)。
[Abstract]:Objective to analyze the distribution and risk factors of nosocomial infection in patients with acute cholecystitis and to provide reference for the prevention and control of nosocomial infection in patients with acute cholecystitis. Methods 410 patients with acute cholecystitis treated in our hospital from January 2014 to June 2016 were selected as study subjects. The nosocomial infection rate and the distribution of pathogenic bacteria were analyzed, and the sex, age and underlying diseases were compared. Interventional therapy and nosocomial infection rate in patients with cholecystolithiasis were analyzed by logistic regression analysis and the relationship between these factors and nosocomial infection in patients with acute cholecystitis. Results among 410 patients with acute cholecystitis, 23 cases were nosocomial infection. The nosocomial infection rate was 5.61%. 31 strains of pathogenic bacteria were isolated from the specimens of 23 cases of acute cholecystitis. Among them, 21 strains of Gram-negative bacteria accounted for 67.74%, 8 strains of Gram-positive bacteria accounted for 25.81% and 2 strains of fungi accounted for 6.45%. The results of univariate analysis showed that sex, age, underlying diseases, Interventional therapy and gallstone were associated with nosocomial infection in patients with acute cholecystitis (P0.05). Multivariate logistic regression analysis showed that sex, age, underlying diseases, Interventional therapy and gallstone are independent risk factors for nosocomial infection in patients with acute cholecystitis. Conclusion Gram-negative bacteria are the main pathogens of nosocomial infection in patients with acute cholecystitis. Sex, age, basic diseases, interventional therapy and gallstone condition are the risk factors for nosocomial infection. Clinical intervention should be carried out according to the above situation.
【作者單位】： 南陽市中心醫(yī)院急診科;
【分類號】：R575.61

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