【摘要】：目的探討新疆地區(qū)維吾爾族人群非酒精性脂肪性肝病(NAFLD)的相關(guān)危險(xiǎn)因素。方法收集新疆醫(yī)科大學(xué)第一附屬醫(yī)院新入院維吾爾族患者及新疆醫(yī)科大學(xué)體檢中心維吾爾族健康體檢者共966例,進(jìn)行問卷調(diào)查及血生化和B超檢查,依據(jù)體檢情況分為NAFLD組(569例)和非NAFLD組(397例);按照體質(zhì)量指數(shù)(BMI)和腰圍身高比值(WHtR)分層對(duì)NAFLD組進(jìn)行危險(xiǎn)因素的相關(guān)性分析。結(jié)果兩組對(duì)象BMI、WHtR比較,差異有統(tǒng)計(jì)學(xué)意義(P0.05);超重(OR=2.527,P0.05)和肥胖(OR=1.938,P0.05)是NAFLD的危險(xiǎn)因素。多因素Logistic回歸分析顯示:BMI、空腹血糖(FPG)和三酰甘油(TG)與NAFLD有關(guān)(P0.05),是NAFLD的危險(xiǎn)因素。結(jié)論BMI、WHtR、FPG和TG是NAFLD的危險(xiǎn)因素,在評(píng)價(jià)和預(yù)測(cè)NAFLD的高危人群中具有一定的臨床意義。
[Abstract]:Objective to investigate the risk factors of (NAFLD) in Uygur population in Xinjiang. Methods A total of 966 newly admitted Uygur patients in the first affiliated Hospital of Xinjiang Medical University and Uygur people in the Medical examination Center of Xinjiang Medical University were investigated by questionnaire and blood biochemistry and B-ultrasound examination. According to the physical examination, the patients were divided into NAFLD group (569 cases) and non-NAFLD group (397 cases), and the risk factors of NAFLD group were analyzed according to body mass index (BMI) and waist height ratio (WHtR) stratification. Results there was significant difference in BMI,WHtR between the two groups (P0.05), and overweight (OR=2.527,P0.05) and obesity (OR=1.938,P0.05) were the risk factors of NAFLD. Multivariate Logistic regression analysis showed that fasting blood glucose (FPG) and triglyceride (TG) were associated with NAFLD (P0.05), which were the risk factors of NAFLD. Conclusion BMI,WHtR,FPG and TG are risk factors for NAFLD, which has clinical significance in evaluating and predicting high risk population of NAFLD.
【作者單位】： 新疆醫(yī)科大學(xué)公共衛(wèi)生學(xué)院勞動(dòng)與環(huán)境衛(wèi)生教研室;新疆維吾爾自治區(qū)婦幼保健醫(yī)院檢驗(yàn)科;新疆醫(yī)科大學(xué)護(hù)理學(xué)院;
【基金】：國(guó)家自然科學(xué)基金資助項(xiàng)目(81460120)
【分類號(hào)】：R575

【參考文獻(xiàn)】

相關(guān)期刊論文 前4條

1 顧偉根;馮靜亞;;超重和肥胖人群非酒精性脂肪肝的流行現(xiàn)狀及相關(guān)危險(xiǎn)因素分析[J];甘肅醫(yī)藥;2015年02期

2 張薇;魏來;;非酒精性脂肪性肝病在亞洲的流行情況[J];中華肝臟病雜志;2013年11期

3 孫建光;呂霞霞;;非酒精性脂肪肝相關(guān)危險(xiǎn)因素分析[J];中醫(yī)臨床研究;2011年18期

4 范建高;周琪;沃千紅;;人體質(zhì)量指數(shù)及其變化與非酒精性脂肪性肝病發(fā)病的關(guān)系[J];中華肝臟病雜志;2010年09期

【共引文獻(xiàn)】

相關(guān)期刊論文 前10條

1 丁園;李艷;;非酒精性脂肪肝患者腎素-血管緊張素系統(tǒng)變化及纈沙坦膠囊對(duì)其影響的研究[J];河北醫(yī)學(xué);2016年12期

2 耿延旭;;淺析治未病理論防治脂肪肝的思路[J];光明中醫(yī);2016年23期

3 郄秋紅;劉躍平;;化濁解毒方對(duì)非酒精性肝病脂肪細(xì)胞因子 瘦素抵抗 胰島素抵抗的影響研究[J];四川中醫(yī);2016年12期

4 咸亞靜;蔡雯;趙艷杰;賴麗君;呂孝臣;林素蘭;;人體測(cè)量學(xué)指標(biāo)與非酒精性脂肪肝的相關(guān)性探討[J];護(hù)士進(jìn)修雜志;2016年15期

5 王新國(guó);黃利華;;空腹運(yùn)動(dòng)對(duì)非酒精性脂肪性肝炎的治療作用[J];世界華人消化雜志;2016年22期

6 尹栩芳;李振軍;施軍平;;細(xì)胞角蛋白18-M30/M65用于中老年脂肪肝篩查的臨床價(jià)值[J];世界華人消化雜志;2016年09期

7 胡中杰;張晶;;我國(guó)非酒精性脂肪性肝病的研究現(xiàn)狀[J];臨床肝膽病雜志;2016年03期

8 王珊;朱國(guó)玲;王謙;佟博;張海玲;張艷敏;吳壽嶺;;體質(zhì)量正常者腰圍變化與新發(fā)非酒精性脂肪肝的關(guān)系[J];實(shí)用醫(yī)學(xué)雜志;2016年04期

9 牛美蘭;田恒運(yùn);馬俊遠(yuǎn);;馬齒莧口服液對(duì)高脂大鼠LEP、ADPN、TC、TG、ALT、AST水平的影響[J];中國(guó)老年學(xué)雜志;2016年01期

10 張e，

本文編號(hào)：2248339