發(fā)布時(shí)間：2018-05-10 13:54

  本文選題：潰瘍性結(jié)腸炎 + 初發(fā)型��； 參考：《新疆醫(yī)科大學(xué)》2014年碩士論文

【摘要】：目的：分析初發(fā)型廣泛型潰瘍性結(jié)腸炎(UC)的臨床特征。方法：回顧性分析新疆維吾爾自治區(qū)人民醫(yī)院2007年5月至2013年3月確診為初發(fā)型UC并住院治療患者的病歷資料,比較廣泛型、直腸型及左半結(jié)腸型患者的民族構(gòu)成比、性別比、診斷時(shí)年齡、居住環(huán)境、疾病嚴(yán)重程度、臨床癥狀、實(shí)驗(yàn)室檢查結(jié)果、結(jié)腸鏡結(jié)果及病理組織學(xué)檢查結(jié)果。三組間比較時(shí),正態(tài)分布資料采用單因素方差分析,偏態(tài)分布資料及等級(jí)資料采用Kruskal-Wallis H檢驗(yàn),計(jì)數(shù)資料采用卡方檢驗(yàn)。結(jié)果：共納入初發(fā)型廣泛型UC患者67例,漢族、維吾爾族及哈薩克族的構(gòu)成比分別為32.8%、58.2%、9.0%,男女性別比為1.48：1,診斷時(shí)的平均年齡為(43.27±16.91)歲,城市與農(nóng)村之比為3.19：1,疾病嚴(yán)重程度以輕度多見(jiàn),輕、中、重度各占56.7%、20.9%、22.4%。癥狀主要以腹痛、腹瀉及黏液膿血便多見(jiàn),部分患者可有發(fā)熱及里急后重,少數(shù)患者伴有腹脹、惡心嘔吐及外周關(guān)節(jié)炎。ESR加快、超敏CRP升高及血漿纖維蛋白原升高分別占37.3%、44.8%、31.3%。與初發(fā)型直腸型UC及初發(fā)型左半結(jié)腸型UC相比,初發(fā)型廣泛型UC患者腹痛、腹瀉、重度、維吾爾族多見(jiàn)及Mayo評(píng)分較高。且腹痛、腹瀉、重度、維吾爾族及Mayo評(píng)分在三組間的兩兩比較中差異有統(tǒng)計(jì)學(xué)意義(P0.017)。結(jié)論：初發(fā)型廣泛型UC以腹痛、腹瀉及維吾爾族多見(jiàn),Mayo評(píng)分較高,疾病嚴(yán)重程度以輕中度為主,與直腸型及左半結(jié)腸型比較,重度明顯增多。
[Abstract]:Objective: to analyze the clinical features of UC- type ulcerative colitis. Methods: the medical records of patients with initial UC diagnosed in Xinjiang Uygur Autonomous region people's Hospital from May 2007 to March 2013 were retrospectively analyzed. The ethnic composition and sex ratio of patients with extensive type, rectum type and left hemicolon type were compared. Age, living environment, severity of disease, clinical symptoms, laboratory findings, colonoscopy and histopathological findings. The normal distribution data were analyzed by single factor ANOVA, the skewness distribution data and grade data were tested by Kruskal-Wallis H test, and the counting data were checked by chi-square test. Results: a total of 67 patients were included in this study. The constituent ratios of Han, Uygur and Kazak nationalities were 32.8and 58.29.0 respectively. The sex ratio of male to female was 1.48: 1. The average age of diagnosis was 43.27 鹵16.91 years old. The ratio of urban to rural is 3.19: 1. The severity of the disease is mild, moderate and severe, accounting for 56.7% and 20.9% respectively. The main symptoms were abdominal pain, diarrhea and mucus abscess. Some of the patients had fever and aggravation. A few patients were accompanied with abdominal distension, nausea and vomiting, peripheral arthritis. ESR was accelerated. The increase of hypersensitive CRP and plasma fibrinogen accounted for 37.3% and 31.3% respectively. Compared with the initial rectal type UC and the initial left hemicolon type UC, the patients with the initial extensive UC had abdominal pain, diarrhea, severe, Uygur, and higher Mayo score. There were significant differences in abdominal pain, diarrhea, severe, Uygur and Mayo scores between the three groups (P 0.017). Conclusion: abdominal pain, diarrhea and Uygur nationality are the most common types of Uygur patients with abdominal pain. The severity of the disease is mainly mild to moderate. Compared with rectum type and left hemicolon type, the severity of UC is obviously increased.
【學(xué)位授予單位】：新疆醫(yī)科大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2014
【分類號(hào)】：R574.62

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