本文選題：Barrett食管　切入點(diǎn)：纖維內(nèi)鏡　出處：《山東醫(yī)藥》2016年31期

【摘要】：Barrett食管(BE)是食管腺癌的癌前病變。傳統(tǒng)診斷BE的方法為常規(guī)內(nèi)鏡檢查結(jié)合病理活檢,但普通內(nèi)鏡可能漏檢早期食管腺癌,且活檢創(chuàng)傷較大,耗時(shí)長(zhǎng),可能產(chǎn)生取材誤差。近年來(lái)一些新的內(nèi)鏡診斷技術(shù)得到開展和應(yīng)用。染色內(nèi)鏡可在一定程度提高BE腸上皮化生、不典型增生的檢出率,但操作相對(duì)繁瑣、耗時(shí)。增強(qiáng)放大內(nèi)鏡能夠提高腸上皮化生的檢出率,單用于診斷BE效果并不理想。窄帶成像技術(shù)(NBI)在診斷BE的異型增生方面有高度準(zhǔn)確性。激光共聚焦顯微內(nèi)鏡(CLE)對(duì)BE中重度不典型增生和黏膜內(nèi)癌的診斷效能較好,但檢查所需時(shí)間和成本較高。食管膠囊內(nèi)鏡(SCE)可以成為診斷BE的重要手段,然而膠囊價(jià)格較為昂貴,且SCE在評(píng)估BE的長(zhǎng)度和類型方面效能一般。光學(xué)相干斷層攝影術(shù)(OCT)和自體熒光成像(AFI)診斷BE的假陽(yáng)性率較高,應(yīng)用受到限制。
[Abstract]:Barrett esophagus is a precancerous lesion of esophageal adenocarcinoma.The traditional method for diagnosis of be is routine endoscopic examination combined with pathological biopsy, but common endoscopy may fail to detect early esophageal adenocarcinoma, and the biopsy is more traumatic and time-consuming, which may result in errors in the selection of materials.In recent years, some new endoscopic diagnostic techniques have been developed and applied.Staining endoscopy can improve the detection rate of be intestinal metaplasia and atypical hyperplasia to some extent, but the operation is relatively cumbersome and time-consuming.Enhanced magnification endoscopy can improve the detection rate of intestinal metaplasia.Narrowband imaging technique (NBI) is highly accurate in the diagnosis of be dysplasia.Laser confocal microendoscopy (CLEs) was effective in the diagnosis of moderate and severe atypical hyperplasia of be and intramucosal carcinoma, but the time and cost of examination were higher.Esophageal capsule endoscopy can be an important method in the diagnosis of be. However, the price of capsule is relatively high, and the efficacy of SCE in evaluating the length and type of be is mediocre.The false positive rate of optical coherence tomography (Oct) and autofluorescence imaging (AFI) in the diagnosis of be is high and its application is limited.
【作者單位】： 貴港市人民醫(yī)院;
【分類號(hào)】：R571

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本文編號(hào)：1696265