本文關鍵詞：肝硬化640層CT肝灌注容積掃描肝血管成像的臨床應用研究　出處：《放射學實踐》2016年12期 　論文類型：期刊論文

  更多相關文章： 肝硬化 灌注成像 血管成像 體層攝影術 X線計算機

【摘要】：目的:探討利用640層CT肝灌注容積數(shù)據(jù)對肝硬化患者進行肝血管成像的可行性及其臨床應用價值。方法:25例肝功正常(A組)和50例肝硬化患者(B組:Child-Pugh A級25例;C組:Child-Pugh B級25例)行640層CT肝灌注檢查,繪制時間-密度曲線(TDC),測量主動脈和門靜脈的達峰值時間(TTP)、峰值(PV)及門靜脈與肝臟密度差的最大值(P-L)。選取主動脈峰值期的容積數(shù)據(jù)進行肝動脈血管成像;采用P-L值最大的1期及3期容積數(shù)據(jù)對門靜脈進行單期和多期融合成像,并對比兩種成像方法的圖像質(zhì)量。結果:三組間主動脈TTP和PV的差異均無統(tǒng)計學意義(P0.05)。肝硬化組門靜脈的TTP較對照組長,PV及P-L值下降,3組間差異有統(tǒng)計學意義(P0.05);進一步兩兩比較,除A與B組間門脈TTP值的差異無統(tǒng)計學意義外,其余各組間3個參數(shù)的差異有統(tǒng)計學意義(P0.05)。3組均可顯示肝動脈3級分支。門脈多期融合成像質(zhì)量優(yōu)于單期成像(P0.05),A組可顯示3~4級門靜脈分支,B和C組可顯示1~3級門靜脈分支。結論:利用640層CT全肝灌注成像容積數(shù)據(jù)進行血管成像,能清晰顯示肝動脈和門靜脈,有助于肝硬化患者臨床治療方案的制訂。
[Abstract]:Objective: to investigate the feasibility and clinical value of hepatic angiography with 640 slice CT perfusion volume data in patients with liver cirrhosis. Methods: 25 patients with normal liver function (group A) and 50 patients with liver cirrhosis (n = 50) were enrolled in this study. Group B: 25 cases of Child-Pugh A grade; Group C: 25 cases with Child-Pugh B grade) underwent 640slice CT hepatic perfusion examination. The time-density curve was plotted and the peak time of aorta and portal vein was measured. Peak PVV) and the maximum density difference between portal vein and liver (P-L). The volume data of peak aortic phase were selected for hepatic artery angiography. One-phase and multi-phase fusion imaging of portal vein was performed by using the volume data of phase 1 and phase 3 with the largest P-L value. Results: there was no significant difference in aortic TTP and PV among the three groups. The TTP of portal vein in cirrhosis group was longer than that in control group. There were significant differences in PV and P-L values among the three groups (P 0.05). Further comparison showed that there was no significant difference in portal TTP between group A and group B. The difference of three parameters among the other groups was statistically significant. The hepatic artery grade 3 branches could be displayed in group P0.05. the quality of portal multi-phase fusion imaging was better than that of single-phase imaging (P0.05). Group A could display 3 grade 4 portal branch B and C group could display 1 grade 3 grade 3 portal vein branch. Conclusion: the total hepatic perfusion volume data of 640 slice CT were used for angiography. It can clearly display hepatic artery and portal vein, which is helpful for the clinical treatment of liver cirrhosis patients.
【作者單位】： 云南省第二人民醫(yī)院放射科;上海復旦大學附屬中山醫(yī)院放射科;
【基金】：云南省教育廳科學研究一般項目(2011Y204)
【分類號】：R575.2;R816.5
【正文快照】： 肝硬化在我國發(fā)病率較高,可并發(fā)肝癌、引起上消化道大出血等而危及患者的生命。全面了解肝臟的代償功能、肝內(nèi)血管及病變的情況,對治療方案的制定和預后評估至關重要。肝灌注成像作為一種功能成像方法,可通過評估肝血流動力學的改變來評估肝臟功能,在臨床應用前景較好。隨著CT

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