【摘要】：目的：探討成人口咽部阻塞平面情況與阻塞性睡眠呼吸暫停低通氣綜合征(OSAHS)的發(fā)病、嚴(yán)重程度及口咽部塌陷程度的相關(guān)性。方法：選擇經(jīng)多導(dǎo)睡眠檢測儀(PSG)檢查符合OSAHS的成人患者62例，記錄患者的睡眠呼吸暫停低通氣指數(shù)(AHI)，最低血氧飽和度(SpO_2)，經(jīng)螺旋CT進(jìn)行口咽部阻塞平面的掃描和測量，并利用電子纖維喉鏡觀測阻塞平面在Muller動(dòng)作下塌陷程度(T)，，確定阻塞平面最小截面積（S）的位置及大小。分析S分別與AHI、最低SpO_2的相關(guān)關(guān)系，并用線性回歸分析上述指標(biāo)的依存性。結(jié)果:①成人口咽部阻塞平面最小截面積（S）多位于口咽部RP區(qū)；②輕、中、重度OSAHS組AHI與S值呈負(fù)相關(guān)性，相關(guān)系數(shù)分別為-0.380、-0.524、-0.633(P0.01)；輕、中、重度OSAHS組的最低SpO_2與S值呈正相關(guān)性，相關(guān)系數(shù)為0.509、0.670、0.529(P0.01)；③塌陷程度(T)與OSAHS患者病情嚴(yán)重程度之間存在明顯的相關(guān)性，F(xiàn)=11.263，P0.01。結(jié)論: AHI、最低SpO_2與S之間存在明顯的相關(guān)性，S的大小影響呼吸暫停低通氣事件的發(fā)生，隨著S的減小，OSAHS患病情嚴(yán)重程度也增加，OSAHS患者發(fā)生睡眠呼吸暫停時(shí)缺氧程度也越嚴(yán)重。本研究可為OSAHS臨床診斷、治療及手術(shù)方法的選擇提供理論依據(jù)與技術(shù)參數(shù)。
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圖片說明：輕度OSAHS組與AHI(次/小時(shí))相關(guān)性分析散點(diǎn)圖
[Abstract]:Objective: to investigate the correlation between pharyngeal obstruction level and the incidence, severity and oropharynx collapse of obstructive sleep apnea hypopnea syndrome (OSAHS). Methods: 62 adult patients with OSAHS were examined by polysomnography (PSG). The minimum oxygen saturation (SpO_2) of (AHI), was recorded. The oropharynx obstruction plane was scanned and measured by spiral CT, and the position and size of (S), the minimum cross section area of obstruction plane, were determined by electronic fiber laryngoscope to observe the collapse degree of blocking plane under Muller action. The correlation between S and AHI, minimum SpO_2 was analyzed, and the dependence of the above indexes was analyzed by linear regression. Results: 1the minimum cross section area of pharynx obstruction plane (S) was mostly located in the oropharynx RP area. (2) there was a negative correlation between AHI and S value in mild, moderate and severe OSAHS groups, the correlation coefficients were-0.380, 鈮

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