【摘要】：目的:應(yīng)用視覺電生理多焦視網(wǎng)膜電流圖(mfERG)的一階函數(shù)核(FOK)檢測高度近視合并黃斑區(qū)脈絡(luò)膜新生血管患者與單純高度近視患者的視網(wǎng)膜功能,并探討兩者之間的差異性。方法:采用隨機(jī)方法選取2015年12月至2016年12月于我院眼科門診確診為高度近視患者40例(60眼)作為研究對象。根據(jù)眼底檢查結(jié)果將以上患者分為2組:實(shí)驗(yàn)組為高度近視合并黃斑區(qū)脈絡(luò)膜新生血管患者20例(30眼);對照組為單純高度近視患者20例(30眼)。以上所有研究對象均接受RETscan3.2視覺電生理儀檢查,記錄多焦視網(wǎng)膜電流圖(mfERG)的一階函數(shù)核(FOK)的波形,以黃斑中心凹區(qū)域的五個環(huán)的正六邊形所對應(yīng)的反應(yīng)波作為研究內(nèi)容,分析P1波與N1波的振幅和潛伏期的改變。對以上結(jié)果行統(tǒng)計學(xué)處理和分析。結(jié)果:1、與單純高度近視對照組相比,高度近視合并黃斑區(qū)脈絡(luò)膜新生血管實(shí)驗(yàn)組在年齡、性別、眼別、高度近視病史、屈光度、眼軸長度方面無明顯差異(P均0.05)。2、與單純高度近視對照組相比,高度近視合并黃斑區(qū)脈絡(luò)膜新生血管實(shí)驗(yàn)組多焦視網(wǎng)膜電流圖P1波環(huán)1到環(huán)5振幅均顯著降低,潛伏期均顯著延遲(P均0.05);N1波環(huán)1到環(huán)5振幅均顯著降低,環(huán)1區(qū)域潛伏期顯著延遲(P均0.05)。結(jié)論:多焦視網(wǎng)膜電流圖檢查能準(zhǔn)確客觀反映高度近視合并黃斑區(qū)脈絡(luò)膜新生血管患者視網(wǎng)膜功能狀態(tài),具有較高的臨床意義。
[Abstract]:Aim: to detect the retinal function of patients with high myopia complicated with macular choroid neovascularization and simple high myopia by using the first order functional nucleus (FOK) of visual electrophysiological multifocal retinal electrography (mfERG), and to explore the difference between them. Methods: from December 2015 to December 2016, 40 patients (60 eyes) with high myopia were randomly selected. According to the results of fundus examination, the patients were divided into two groups: 20 patients (30 eyes) with high myopia complicated with macular choroid neovascularization in the experimental group and 20 patients (30 eyes) in the control group with simple high myopia. All the above subjects were examined by RETscan3.2 visual electrophysiology instrument. The first-order functional kernel (FOK) waveforms of multifocal retinal electrogram (mfERG) were recorded. The response waves corresponding to the regular hexagonal of five rings in the macular fovea were taken as the research content to analyze the changes of amplitude and latency of P1 wave and N1 wave. The above results were statistically analyzed and analyzed. Results: 1. Compared with the control group, there was no significant difference in age, sex, eye difference, history of high myopia, diopter and axial length between the experimental group and the control group (P 0.05). 2, compared with the control group, there was no significant difference in age, sex, eye difference, history of high myopia, diopter and axial length between the experimental group and the control group. In the experimental group of choroid neovascularization in high myopia complicated with macular area, the amplitudes of P1 wave loop 1 to ring 5 were significantly decreased and the latency was significantly delayed (P 0.05). The amplitudes of N1 wave ring 1 to ring 5 were significantly decreased, and the latency of ring 1 region was significantly delayed (P 0.05). Conclusion: multifocal retinal electrography can accurately and objectively reflect the retinal function of patients with high myopia complicated with macular choroid neovascularization, and has high clinical significance.
【學(xué)位授予單位】：南昌大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2017
【分類號】：R778.11;R773.4

【參考文獻(xiàn)】

相關(guān)期刊論文 前5條

1 高瑞新;李朝霞;;多焦視網(wǎng)膜電流圖用于近視眼視網(wǎng)膜功能的研究[J];眼科新進(jìn)展;2012年03期

2 王煥榮;趙樂;;380例高度近視眼多焦視網(wǎng)膜電圖特點(diǎn)[J];中國斜視與小兒眼科雜志;2010年02期

3 羅俊;劉雙珍;吳小影;夏朝華;;高度近視患者多焦視網(wǎng)膜電流圖的評估[J];國際眼科雜志;2006年06期

4 孫秀英;李建軍;王鈺;徐亮;;近視對多焦視網(wǎng)膜電圖一階反應(yīng)的影響[J];中華眼底病雜志;2006年02期

5 鐘興武,葛堅(jiān),楊曉,龔向明,陳景榮,梁丹;近視眼的多焦視網(wǎng)膜電流圖改變[J];中國實(shí)用眼科雜志;2001年05期

，

本文編號：2507769