健康年輕人慢跑前后前房形態(tài)的變化
發(fā)布時間：2019-06-18 22:56
【摘要】：目的 分析Pentacam三維眼前節(jié)分析儀測量健康年輕志愿者前房容積（anterior chambervolume，ACV）、中央前房深度（central anterior chamber depth，CACD）、周邊前房深度（peripheral anterior chamber depth，PACD）、前房角（anterior chamber angle，ACA）、瞳孔直徑（pupil diameter，PD）等前房形態(tài)生物學(xué)參數(shù)的重復(fù)性。方法 于2011年10月-2011年11月連續(xù)收集健康志愿者30例（30只眼），年齡18～27歲。其中，男性15例（平均年齡22.56±3.31歲），女性15例（平均年齡20.57±1.78歲）。使用Pentacam三維眼前節(jié)分析儀連續(xù)測量前房形態(tài)3次，，選取Qs為OK的3次測量結(jié)果。采用SPSS13.0統(tǒng)計軟件對數(shù)據(jù)進(jìn)行處理。首先對數(shù)據(jù)進(jìn)行Shapiro-Wilk正態(tài)分布檢驗，并用正態(tài)Q-Q圖（Normal Q-Q Plots）對前房形態(tài)各生物學(xué)參數(shù)數(shù)據(jù)分別進(jìn)行繪圖；采用組內(nèi)相關(guān)系數(shù)（intraclass correlation coefficients，ICC）評估Pentacam三維眼前節(jié)分析儀測量前房形態(tài)的重復(fù)性；并對前房形態(tài)各生物學(xué)參數(shù)的3組數(shù)據(jù)進(jìn)行相關(guān)性分析。 結(jié)果 對前房形態(tài)各生物學(xué)參數(shù)數(shù)據(jù)進(jìn)行Shapiro-Wilk正態(tài)分布檢驗，P值（Sig.）均＞0.01，提示呈正態(tài)分布。Pentacam三維眼前節(jié)分析儀對30只正常眼連續(xù)測量3次的結(jié)果分析，ACV、CACD、PACD0°、PACD90°、PACD180°、PACD270°、ACA、PD的組內(nèi)相關(guān)系數(shù)ICC分別為0.986、0.985、0.989、0.954、0.989、0.991、0.956、0.929。前房形態(tài)各生物學(xué)參數(shù)的3組數(shù)據(jù)進(jìn)行相關(guān)性分析顯示，三次測量之間彼此存在高度相關(guān)性，r值均大于0.800（雙側(cè)P值均為0.000）。 結(jié)論 Pentacam三維眼前節(jié)分析儀測量健康年輕志愿者的前房容積、中央前房深度、周邊前房深度、前房角時重復(fù)性好，表現(xiàn)出較好的一致性。在測量瞳孔直徑時重復(fù)性欠良好，可能與儀器原理方面和（或）生理因素有關(guān)。 目的 使用Pentacam三維眼前節(jié)分析儀測量健康年輕人慢跑前后中央前房深度、周邊前房深度、前房容積、前房角、瞳孔直徑的大小，量化分析其變化規(guī)律，為前房形態(tài)動態(tài)變化研究提供資料。 方法 58例健康志愿者（58眼），男性16例（平均年齡22.56±3.31歲），女性42例（平均年齡20.57±1.78歲），排除眼部器質(zhì)性疾病及全身系統(tǒng)性疾病。按照Karvonen方法慢跑20min，慢跑前、慢跑結(jié)束停止瞬間0min及之后5min、15min、30min、60min使用Pentacam三維眼前節(jié)分析儀觀察前房形態(tài)，其生物學(xué)參數(shù)包括前房容積（anteriorchamber volume，ACV）、中央前房深度（central anterior chamber depth，CACD）、周邊前房深度（peripheral anterior chamber depth，PACD）、前房角（anterior chamber angle，ACA）、瞳孔直徑（pupil diameter，PD），同時使用非接觸眼內(nèi)壓計測眼內(nèi)壓（intraocularpressure，IOP）、IOL-Master測量眼軸長度（axial length，AL）。應(yīng)用SPSS13.0軟件統(tǒng)計分析，首先對各參數(shù)在不同時間點的數(shù)據(jù)進(jìn)行Lilliefors正態(tài)性檢驗；對各參數(shù)在不同時間點測量的數(shù)據(jù)進(jìn)行重復(fù)測量設(shè)計的方差分析；用重復(fù)測量數(shù)據(jù)多重比較配對t檢驗法（Bonferroni法）對各參數(shù)在不同時間點數(shù)值進(jìn)行兩兩比較；對慢跑前后各參數(shù)的變化進(jìn)行直線相關(guān)分析。 結(jié)果 慢跑20min后，前房容積、中央前房深度、周邊前房深度、前房角、瞳孔直徑、眼內(nèi)壓、眼軸長度均有變化，且在慢跑停止瞬間0min變化最明顯。前房容積增加(188.38±25.87μl/198.03±27.32μl, P＜0.05)，中央前房深度加深（3.19±0.25mm/3.21±0.25mm,P＜0.05），周邊前房深度加深（2.37±0.25mm/2.43±0.25mm,P＜0.05），前房角變�。�41.59±4.91°/40.69±4.68°,P＜0.05），瞳孔直徑增大（2.98±0.38mm/3.34±0.59mm,P＜0.05），眼內(nèi)壓降低（14.50±2.87mm/12.78±2.51mm,P＜0.05），眼軸長度增長（24.95±0.89mm/24.97±0.89mm,P＜0.05）。慢跑前后前房容積的變化與周邊前房深度的變化之間有相關(guān)關(guān)系，相關(guān)系數(shù)r值=0.565，為中度相關(guān)，即前房容積的變化與周邊前房深度的變化呈正相關(guān)。中央前房深度的變化與周邊前房深度的變化之間有相關(guān)關(guān)系，相關(guān)系數(shù)r值為0.392，即二者呈正相關(guān)。 結(jié)論 慢跑20min后前房深度加深、前房容積增加、瞳孔直徑增大，同時伴眼軸長度增長，提示慢跑可以引起前房形態(tài)的動態(tài)變化，降低眼內(nèi)壓。其機(jī)制是否為血液動力學(xué)因素變化導(dǎo)致的脈絡(luò)膜厚度變薄影響眼內(nèi)容體積，需要進(jìn)一步的研究證實。
[Abstract]:Purpose The anterior chamber volume (ACV), central anterior chamber depth (CACD), peripheral anterior chamber depth (PACD), anterior chamber angle (ACA), and pupil diameter (ppuil diaminete) were measured. Repetition of biological parameters in anterior chamber, such as r (PD) Sex. Methods 30 cases (30 eyes) of healthy volunteers were collected from October 2011 to November 2011, and the age of 18 ~ 27 years old, of which 15 (mean age: 22.56, 3.31 years) and 15 women (mean age 20.57%) 8-year-old).3 times of anterior chamber morphology were continuously measured using a Penacam three-dimensional anterior segment analyzer, and three measurements of Qs as OK were selected Volume results. Data entry using the SPSS13.0 statistical software The data was first examined by Shapiro-Wilk normal distribution and the biological parameters of the anterior chamber were plotted by normal Q-Q (Normal Q-Q Plots). The anterior chamber morphology of the anterior chamber was measured by using the intra-group correlation coefficient (ICC) to evaluate the anterior chamber morphology of the Penta 3-D anterior segment. Repeatability; and related to 3 sets of data for each biological parameter in the anterior chamber sex Analysis of the biological parameters of the anterior chamber with Shapiro-Wilk normal distribution test , the P value (Sig.) is greater than 0.01, The results of 3 times of continuous measurement of 30 normal eyes were analyzed, and the correlation coefficient (ICC) of ACV, CACD, PACD0 擄, PACD90 擄, PACD180 擄, PACD270 擄, ACA and PD was 0.986, 0.985, 0.989, 0.954, 0.989, 0.991, 0.95, respectively. 6. The correlation analysis between the three groups of the biological parameters of the anterior chamber morphology showed that there was a high correlation between the three measurements, and the r value was greater than 0.800 (bilateral P value 0 .000). Conclusion Penacam three-dimensional anterior segment analyzer measures the anterior chamber volume, central anterior chamber depth, peripheral anterior chamber depth, anterior chamber angle, and repeatability of healthy young volunteers Good, good consistency. The repeatability is good at the time of measuring the diameter of the pupil, which may be related to the principle of the instrument face and (or) related to physiological factors. The purpose of this study was to measure the changes of the anterior chamber depth, the anterior chamber depth, the anterior chamber volume, the anterior chamber angle and the pupil diameter before and after jogging in healthy young people using the Penacam three-dimensional anterior segment analyzer. in front of Methods 58 healthy volunteers (58 eyes),16 males (mean age 22.56 and 3.31 years) and 42 females (mean age of 20.57 and 1.78 years) were provided. ), excluding the organic and systemic diseases of the eye, jogging for 20 minutes according to the Karvonen method, jogging, stopping for 0 minutes and then 5 minutes,15 minutes,30 minutes, and 60 minutes using the Penacam three-dimensional anterior segment analyzer to observe the morphology of the anterior chamber, the biological parameters of the anterior chamber volume (ACV) and the central anterior chamber depth (central anterio). R-chamber depth (CACD), peripheral anterior chamber depth (PACD), anterior chamber angle (ACA), and pupil diameter (PD). The axial length (AL). The software of the SPSS13.0 software is used for statistical analysis, and the data of each parameter at different time points is first tested by Lillifors; for each parameter at different time the data of the point measurement is subjected to the analysis of variance of the repeated measurement design; the value of each parameter at different time points is compared by using the repeated measurement data multiple-comparison paired t-test method (Bonferroni method); slow-to-slow After 20 minutes of jogging, the anterior chamber volume, the central anterior chamber depth, the peripheral anterior chamber depth, the anterior chamber angle, the pupil diameter, the intraocular pressure, the eye axis length, The changes of anterior chamber volume (188.38, 25.87 & mu; l/ 198.03, 27.32 & mu; l, P <0.05), deep anterior chamber depth (3.19, 0.25 mm/ 3.21, 0.25 mm, P <0.05), and peripheral anterior chamber depth (2.37, 0.25 mm/ 2.43, 0.25 mm, P <0.05), and small anterior chamber angle (41.59%). 91 擄/ 40.69 (4.68 擄, P <0.05), pupil diameter increased (2.98, 0.38 mm/ 3.34, 0.59 mm, P <0.05), intraocular pressure decreased (14.50, 2.87 mm/ 12.78, 2.51 mm, P <0.05), and the length of the eye (24.95) 0.89 Mm/ 24.97 (0.89 mm, P <0.05). There was a correlation between the changes in the volume of the anterior chamber before and after the jogging and the change in the depth of the anterior chamber. The correlation coefficient, r, was 0.565, which was moderate. The change of the anterior chamber volume is positively correlated with the change of the anterior chamber depth. The change of the anterior chamber depth is related to the change of the anterior chamber depth. relationship The results showed that the depth of the anterior chamber, the volume of the anterior chamber, the diameter of the pupil and the length of the eye were increased after 20 minutes of jogging. The results suggest that jogging can cause the dynamic changes of the morphology of the anterior chamber and decrease the intraocular pressure. The mechanism of the mechanism is the change of hemodynamics.
【學(xué)位授予單位】：泰山醫(yī)學(xué)院
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2012
【分類號】：R775
本文編號：2501860
[Abstract]:Purpose The anterior chamber volume (ACV), central anterior chamber depth (CACD), peripheral anterior chamber depth (PACD), anterior chamber angle (ACA), and pupil diameter (ppuil diaminete) were measured. Repetition of biological parameters in anterior chamber, such as r (PD) Sex. Methods 30 cases (30 eyes) of healthy volunteers were collected from October 2011 to November 2011, and the age of 18 ~ 27 years old, of which 15 (mean age: 22.56, 3.31 years) and 15 women (mean age 20.57%) 8-year-old).3 times of anterior chamber morphology were continuously measured using a Penacam three-dimensional anterior segment analyzer, and three measurements of Qs as OK were selected Volume results. Data entry using the SPSS13.0 statistical software The data was first examined by Shapiro-Wilk normal distribution and the biological parameters of the anterior chamber were plotted by normal Q-Q (Normal Q-Q Plots). The anterior chamber morphology of the anterior chamber was measured by using the intra-group correlation coefficient (ICC) to evaluate the anterior chamber morphology of the Penta 3-D anterior segment. Repeatability; and related to 3 sets of data for each biological parameter in the anterior chamber sex Analysis of the biological parameters of the anterior chamber with Shapiro-Wilk normal distribution test , the P value (Sig.) is greater than 0.01, The results of 3 times of continuous measurement of 30 normal eyes were analyzed, and the correlation coefficient (ICC) of ACV, CACD, PACD0 擄, PACD90 擄, PACD180 擄, PACD270 擄, ACA and PD was 0.986, 0.985, 0.989, 0.954, 0.989, 0.991, 0.95, respectively. 6. The correlation analysis between the three groups of the biological parameters of the anterior chamber morphology showed that there was a high correlation between the three measurements, and the r value was greater than 0.800 (bilateral P value 0 .000). Conclusion Penacam three-dimensional anterior segment analyzer measures the anterior chamber volume, central anterior chamber depth, peripheral anterior chamber depth, anterior chamber angle, and repeatability of healthy young volunteers Good, good consistency. The repeatability is good at the time of measuring the diameter of the pupil, which may be related to the principle of the instrument face and (or) related to physiological factors. The purpose of this study was to measure the changes of the anterior chamber depth, the anterior chamber depth, the anterior chamber volume, the anterior chamber angle and the pupil diameter before and after jogging in healthy young people using the Penacam three-dimensional anterior segment analyzer. in front of Methods 58 healthy volunteers (58 eyes),16 males (mean age 22.56 and 3.31 years) and 42 females (mean age of 20.57 and 1.78 years) were provided. ), excluding the organic and systemic diseases of the eye, jogging for 20 minutes according to the Karvonen method, jogging, stopping for 0 minutes and then 5 minutes,15 minutes,30 minutes, and 60 minutes using the Penacam three-dimensional anterior segment analyzer to observe the morphology of the anterior chamber, the biological parameters of the anterior chamber volume (ACV) and the central anterior chamber depth (central anterio). R-chamber depth (CACD), peripheral anterior chamber depth (PACD), anterior chamber angle (ACA), and pupil diameter (PD). The axial length (AL). The software of the SPSS13.0 software is used for statistical analysis, and the data of each parameter at different time points is first tested by Lillifors; for each parameter at different time the data of the point measurement is subjected to the analysis of variance of the repeated measurement design; the value of each parameter at different time points is compared by using the repeated measurement data multiple-comparison paired t-test method (Bonferroni method); slow-to-slow After 20 minutes of jogging, the anterior chamber volume, the central anterior chamber depth, the peripheral anterior chamber depth, the anterior chamber angle, the pupil diameter, the intraocular pressure, the eye axis length, The changes of anterior chamber volume (188.38, 25.87 & mu; l/ 198.03, 27.32 & mu; l, P <0.05), deep anterior chamber depth (3.19, 0.25 mm/ 3.21, 0.25 mm, P <0.05), and peripheral anterior chamber depth (2.37, 0.25 mm/ 2.43, 0.25 mm, P <0.05), and small anterior chamber angle (41.59%). 91 擄/ 40.69 (4.68 擄, P <0.05), pupil diameter increased (2.98, 0.38 mm/ 3.34, 0.59 mm, P <0.05), intraocular pressure decreased (14.50, 2.87 mm/ 12.78, 2.51 mm, P <0.05), and the length of the eye (24.95) 0.89 Mm/ 24.97 (0.89 mm, P <0.05). There was a correlation between the changes in the volume of the anterior chamber before and after the jogging and the change in the depth of the anterior chamber. The correlation coefficient, r, was 0.565, which was moderate. The change of the anterior chamber volume is positively correlated with the change of the anterior chamber depth. The change of the anterior chamber depth is related to the change of the anterior chamber depth. relationship The results showed that the depth of the anterior chamber, the volume of the anterior chamber, the diameter of the pupil and the length of the eye were increased after 20 minutes of jogging. The results suggest that jogging can cause the dynamic changes of the morphology of the anterior chamber and decrease the intraocular pressure. The mechanism of the mechanism is the change of hemodynamics.
【學(xué)位授予單位】：泰山醫(yī)學(xué)院
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2012
【分類號】：R775
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