【摘要】：目的分析及比較對于濕性老年性黃斑變性實施雷珠單抗、康柏西普治療的效果。方法選取2015年6月~2016年6月我院收治的濕性老年性黃斑變性患者60例,隨機分成A組和B組,各30例。應(yīng)用雷珠單抗治療為A組,應(yīng)用康柏西普治療為B組,觀察及統(tǒng)計經(jīng)不同治療方案以后獲的效果。結(jié)果經(jīng)治療,同應(yīng)用康柏西普治療的B組相比較,應(yīng)用雷珠單抗治療的A組患者的視力更高,同時黃斑中心凹視網(wǎng)膜厚度更薄,差異有統(tǒng)計學(xué)意義(P0.05);進行注射4周和12周以后,對CNV滲漏的治療兩組均具有明顯效果,差異有統(tǒng)計學(xué)意義(P0.05)。結(jié)論康柏西普治療濕性老年性黃斑變性獲得的CNV滲漏減輕效果同雷珠單抗治療的效果相當(dāng),但是對于改善視力和黃斑中心凹視網(wǎng)膜厚度效果較差,隨時間的增加,可達到療效相同。
[Abstract]:Objective to analyze and compare the efficacy of Rayzumab and Compaximab in the treatment of wet age-related macular degeneration. Methods from June 2015 to June 2016, 60 patients with wet age-related macular degeneration were randomly divided into two groups: group A (n = 30) and group B (n = 30). Group A was treated with Rayzumab and group B was treated with Compaximab. The effects of different treatment schemes were observed and counted. Results after treatment, the visual acuity and retinal thickness of macular fovea in group A were significantly higher than those in group B treated with Compaximab (P0.05), and the visual acuity and retinal thickness of macular fovea in group A were higher than those in group B treated with Compaximab (P0.05). After 4 weeks and 12 weeks of injection, the treatment of CNV leakage in both groups had a significant effect, the difference was statistically significant (P0.05). Conclusion Compaximab can reduce the leakage of CNV in patients with wet age-related macular degeneration, but it is less effective in improving visual acuity and macular fovea thickness with the increase of time, and the effect of Compaximab is similar to that of Rayzumab in treating wet age-related macular degeneration. Can achieve the same curative effect.
【作者單位】： 齊齊哈爾市第一醫(yī)院病房西藥局;
【分類號】：R774.5

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