糖尿病視網膜病變進展的危險因素分析
[Abstract]:Objective to study the risk factors of progression of diabetic retinopathy. Methods the clinical data of 137 diabetic patients admitted from July 2012 to July 2015 were retrospectively analyzed. According to the retinopathy of diabetic patients, the patients were divided into 3 groups, 43 patients without retinopathy as control group. 46 cases of non-proliferative retinopathy as observation group, 48 cases of proliferative retinopathy as experimental group. The blood pressure, blood glucose, glycosylated hemoglobin, blood lipids and albumin creatinine ratio were analyzed. Multivariate logistic regression analysis was used to observe the risk factors for progression of diabetic retinopathy. Results the glycosylated hemoglobin, total cholesterol, triacylglycerol, low density lipoprotein cholesterol, high density lipoprotein cholesterol, body mass index, 2 h postprandial blood glucose and fasting blood glucose were not significantly different (P0.05). The duration of the disease, angiopoietin 2, vascular endothelial growth factor and urinary albumin creatinine ratio between groups, the differences were statistically significant (P0.05); Multivariate logistic regression analysis showed that diabetes course, glycosylated hemoglobin, systolic blood pressure, urinary albumin creatinine ratio and vascular endothelial growth factor were significantly correlated with diabetic retinopathy (P0.05). Conclusion the progression of diabetic retinopathy can be caused by the increase of course of diabetes, unstable blood glucose, unstable blood pressure, and the increase of angiopoietin 2 and vascular endothelial growth factor.
【作者單位】: 滕州市中心人民醫(yī)院眼科;
【分類號】:R587.2;R774.1
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