【摘要】：【目的】對Q值引導個性化LASIK（Q-value guided custiomizedLASIK， Q-LASIK）及標準化LASIK（Standardized LASIK， S-LASIK）兩種手術(shù)方式在近視治療上的臨床效果進行回顧性比較與分析。 【方法】選取2011年5月至2012年2月間于我院行Q-LASIK術(shù)后3個月20例40眼，S-LASIK術(shù)后術(shù)后3個月20例40眼。隨訪并比較分析術(shù)前1周和術(shù)后1個月及術(shù)后3個月時患者的裸眼視力、矯正視力、屈光度、角膜Q值及患者主觀感受滿意度。 【結(jié)果】兩組術(shù)前及術(shù)后隨訪結(jié)果：（1）安全性：Q-LASIK術(shù)后3月無1例出現(xiàn)最佳矯正視力下降，S-LASIK僅有1例下降，安全性指數(shù)分別為1.047和1.024；（2）有效性：術(shù)后3月兩組裸眼視力均大于等于1.0，均達到預期值，有效性指數(shù)均約為0.99；（3）可靠性：術(shù)后1月～術(shù)后3月，兩組術(shù)后等效球鏡度均無明顯改變，，兩組間比較無統(tǒng)計學差異(P0.05)；（4）術(shù)后3月歲讓，兩組Q值叫術(shù)前均明顯增加（P0.05），Q-LASIK組增加值△Q明顯低于S-LASIK組(P0.05)；（5）術(shù)后1周及3月隨訪，Q-LASIK組主觀視覺質(zhì)量反饋較S-LASIK組稍高（P0.05）。 【結(jié)論】通過比較發(fā)現(xiàn)兩種術(shù)式的安全性、有效性及可靠性均較好，均可有效的改善近視患者的視覺；而Q-LASIK術(shù)式相較S-LASIK術(shù)式，術(shù)后角膜形態(tài)改變較少，且差異較顯著；患者主觀視覺感受上Q-LASIK組更佳。為了跟進一步量化評價兩種手術(shù)在視覺質(zhì)量上的差別，還需要跟多的病例及更全面的評價指標，例如對比敏感度等。
[Abstract]:[objective] to compare and analyze the clinical effect of Q guided individualized LASIK (Q-value guided custiomizedLASIK, Q-LASIK) and standardized LASIK (Standardized LASIK, S-LASIK in myopia treatment. [methods] from May 2011 to February 2012, 20 cases (40 eyes) and 20 cases (40 eyes) were treated with Q-LASIK in our hospital 3 months after operation and 3 months after S-LASIK. The uncorrected visual acuity, corrected visual acuity, diopter, corneal Q value and subjective feeling satisfaction of the patients were compared and analyzed 1 week before operation, 1 month after operation and 3 months after operation. [results] the two groups were followed up before and after operation: (1) Safety: no case had the decline of best corrected visual acuity (BCVA) in 3 months after Q-LASIK, only 1 case of S-LASIK decreased, the safety index was 1.047 and 1.024 respectively. (2) effectiveness: the uncorrected visual acuity of the two groups was more than 1.0 at 3 months after operation, reaching the expected value, and the validity index was about 0.99; (3) Reliability: from 1 month to 3 months after operation, there was no significant change in the equivalent spherical degree between the two groups, and there was no statistical difference between the two groups (P0.05). (4) at the age of 3 months after operation, the Q value of the two groups increased significantly before operation (P0.05), and that of the Q-LASIK group was significantly lower than that of the S-LASIK group (P0.05). (5) after 1 week and 3 months follow-up, subjective visual quality feedback in Q-LASIK group was slightly higher than that in S-LASIK group (P0.05). [conclusion] it is found that the two methods are safe, effective and reliable, and can improve the vision of myopia patients effectively, but the corneal morphology of Q-LASIK is less than that of S-LASIK, and the difference is significant. Q-LASIK group was better in subjective visual perception. In order to compare with the further quantitative evaluation of the visual quality of the two operations, it is necessary to have more cases and more comprehensive evaluation indicators, such as contrast sensitivity, etc.
【學位授予單位】：重慶醫(yī)科大學
【學位級別】：碩士
【學位授予年份】：2012
【分類號】：R779.63

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1 徐莉;錢濤;李一壯;;非球面?zhèn)�體化切削LASIK與傳統(tǒng)LASIK術(shù)后視覺效果的比較(英文)[J];國際眼科雜志;2007年03期

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