【摘要】：目的動(dòng)態(tài)觀察大前庭水管綜合征(large vestibular aqueduct syndrome,LVAS)患者的聽力變化,為更好地保護(hù)LVAS患者的聽力提供參考。方法選取2007年7月至2016年5月經(jīng)確診且資料完整、能夠準(zhǔn)確完成純音聽閾檢測的雙耳大前庭水管綜合征患者21例為研究對象,年齡5~29歲,中位年齡11歲,其中男12例,女9例;12例患者行單側(cè)人工耳蝸植入手術(shù),另一耳佩戴助聽器,其余患者均雙耳佩戴助聽器。動(dòng)態(tài)觀察非耳蝸植入耳聽力2~7年,中位數(shù)3年4個(gè)月;在隨訪期間發(fā)現(xiàn)患者聽力下降就診,及時(shí)給予擴(kuò)血管改善循環(huán)、營養(yǎng)神經(jīng)等藥物保守治療1~2周,比較用藥前后的聽力變化;病情穩(wěn)定者一年復(fù)查一次純音聽閾,動(dòng)態(tài)觀察聽力變化。結(jié)果21例(30耳)中隨訪期間有15例發(fā)生過聽力波動(dòng)(下降),治療前500、1 000、2 000、4 000 Hz平均純音聽閾分別為85.3±4.4、91.5±4.3、95.9±5.7、99.1±6.6dB HL,治療后分別為66.5±4.1、74.4±4.1、76.8±5.0、80±5.9dB HL,各頻率治療前后比較差異均有統(tǒng)計(jì)學(xué)意義(均為P0.05)。結(jié)論大前庭水管綜合征患者可表現(xiàn)為波動(dòng)性或進(jìn)行性感音神經(jīng)性聽力損失;早期發(fā)現(xiàn)、及時(shí)治療,可使LVAS患者的聽力維持在一定的水平或使之聽力下降的速度明顯減緩。
[Abstract]:Objective to observe the dynamic changes of hearing in patients with large vestibular aqueduct syndrome (large vestibular aqueduct syndrome,LVAS) and to provide reference for the better protection of the hearing of patients with large vestibular aqueduct syndrome (LVAS). Methods from July 2007 to May 2016, 21 patients with binaural great vestibular aqueduct syndrome who were diagnosed from July 2007 to May 2016 and whose data were complete accurately, including 12 males and 9 females, aged 529 years with a median age of 11 years, were selected. Unilateral cochlear implantation was performed in 12 patients, hearing aids were used in the other ear, and hearing aids were used in both ears. The hearing of non-cochlear implants was observed dynamically for 27 ~ 7 years, with a median of 3 years and 4 months. During the follow-up period, we found that the patients with hearing loss were treated with vasodilator to improve circulation and nutrition nerve for 1 to 2 weeks. The hearing changes before and after treatment were compared. The patients with stable condition rechecked the pure tone hearing threshold once a year and observed the change of hearing dynamically. Results during the follow-up period of 21 cases (30 ears), 15 cases had hearing fluctuation (decline). Before treatment, the mean pure tone hearing threshold was 85.3 鹵4.4 鹵94. 5 鹵5. 799.1 鹵5. 799.1 鹵5. 799.1 Hz, respectively. After treatment, there were significant differences in the frequency of treatment (66.5 鹵4.1) and 74.4 鹵4.1 (76.8 鹵5.0 鹵80 鹵5.9dB HL,) before and after treatment (P0.05). Conclusion the patients with large vestibular aqueduct syndrome may exhibit volatile or sensual hearing loss, and the early detection and timely treatment can significantly slow down the hearing loss or maintain a certain level of hearing in patients with LVAS.
【作者單位】： 安徽省立醫(yī)院耳鼻咽喉頭頸外科;
【分類號(hào)】：R764

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