上石疽的辯證分型及臨床病理研究
發(fā)布時間:2018-09-10 17:18
【摘要】:目的:通過組織病理學(xué)手段探討鼻咽癌頸淋巴結(jié)的轉(zhuǎn)移情況與大小關(guān)系。 方法: 收集我院1992年11月~2011年5月未治的鼻咽癌且行頸部淋巴結(jié)活檢術(shù)(或全頸/局部頸淋巴結(jié)清掃術(shù))病例30例,分析術(shù)后病理記錄的淋巴結(jié)轉(zhuǎn)移情況與其最大徑、最短徑等之間的關(guān)系。 結(jié)果: 1.病理分型結(jié)果 30份術(shù)后標(biāo)本,按照WHO2003年鼻咽癌鏡下分型,其中非角化型癌30例。 2.淋巴結(jié)的大小與轉(zhuǎn)移的情況 全組共收集淋巴結(jié)55枚,經(jīng)病理核實陽性淋巴結(jié)46個,轉(zhuǎn)移率83.6%(46/55)淋巴結(jié)的分布以Ⅱ~Ⅴ區(qū)為主:Ⅰ區(qū)淋巴結(jié)共6枚,轉(zhuǎn)移率為100%,而Ⅱ~Ⅴ淋巴結(jié)49枚(因無完整影像資料,無法區(qū)分具體分區(qū)),陽性淋巴結(jié)40個,轉(zhuǎn)移率81.6%(40/49),無咽后淋巴結(jié);全組淋巴結(jié),短徑2~45mm,中位數(shù):23.5mm,其中短徑lOmm的淋巴結(jié)有24枚,病理顯示轉(zhuǎn)移淋巴結(jié)19個,轉(zhuǎn)移率79.2%(19/24),而短徑≥10mm的淋巴結(jié)有31個,陽性淋巴結(jié)27個,轉(zhuǎn)移率87.1%(27/31),短徑≥10mm組和≥8mm組分別作為診斷標(biāo)準(zhǔn)所得全組淋巴結(jié)的敏感性、特異性、準(zhǔn)確性、陽性預(yù)測值及陰性預(yù)測值分別為:58.7%、55.6%、58.2%、87.1%、20.8%和69.6%、55.6%、67.3%、88.9%、26.3%,短徑≥8mm組各指標(biāo)均優(yōu)于短徑≥10mm組,但差異無統(tǒng)計學(xué)意義(P0.05) 3.簇集狀淋巴結(jié)轉(zhuǎn)移情況 4組呈簇集淋巴結(jié)共18枚,轉(zhuǎn)移淋巴結(jié)15個,轉(zhuǎn)移率83.3%,其中短徑≥8mm的淋巴結(jié)4個,轉(zhuǎn)移率100%(4/4),而短徑8mmm的淋巴結(jié)14個,轉(zhuǎn)移淋巴結(jié)11個,轉(zhuǎn)移率78.6%(11/14),其中短徑分布在5~8mm的淋巴結(jié)數(shù)目為0,短徑≥8mm和8mm組淋巴結(jié)所得敏感性、特異性、準(zhǔn)確性、陽性預(yù)測值及陰性預(yù)測值分別是26.7%、100%、38.9%、100%、21.4%和26.7%、0%、61.1%、78.6%、0%,兩者之間P0.05。 結(jié)論: 鼻咽癌頸淋巴結(jié)轉(zhuǎn)移率高,這可能于淋巴結(jié)取樣標(biāo)本多來源于頸部淋巴結(jié)摘除活檢術(shù)有關(guān),其中短徑10mm的淋巴結(jié)也存在較高的轉(zhuǎn)移率,需臨床醫(yī)師重視,把短徑≥8mm作為簇集狀淋巴結(jié)的診斷標(biāo)準(zhǔn)是合理的。
[Abstract]:Objective: to investigate the relationship between metastasis and size of cervical lymph nodes in nasopharyngeal carcinoma by histopathological methods. Methods: from November 1992 to May 2011, 30 patients with nasopharyngeal carcinoma underwent cervical lymph node biopsy (or total neck / local neck lymph node dissection). To analyze the relationship between lymph node metastasis and its maximum and shortest diameter. Results: 1. Pathological classification results of 30 postoperative specimens, according to the WHO2003 age of nasopharyngeal carcinoma classification under the microscope, including 30 cases of non-keratinized carcinoma. 2. The size and metastasis of lymph nodes were collected from 55 lymph nodes in the whole group. 46 positive lymph nodes were confirmed by pathology. The metastatic rate was 83.6% (46 / 55). The distribution of lymph nodes was mainly in 鈪,
本文編號:2235102
[Abstract]:Objective: to investigate the relationship between metastasis and size of cervical lymph nodes in nasopharyngeal carcinoma by histopathological methods. Methods: from November 1992 to May 2011, 30 patients with nasopharyngeal carcinoma underwent cervical lymph node biopsy (or total neck / local neck lymph node dissection). To analyze the relationship between lymph node metastasis and its maximum and shortest diameter. Results: 1. Pathological classification results of 30 postoperative specimens, according to the WHO2003 age of nasopharyngeal carcinoma classification under the microscope, including 30 cases of non-keratinized carcinoma. 2. The size and metastasis of lymph nodes were collected from 55 lymph nodes in the whole group. 46 positive lymph nodes were confirmed by pathology. The metastatic rate was 83.6% (46 / 55). The distribution of lymph nodes was mainly in 鈪,
本文編號:2235102
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