【摘要】：目的了解醫(yī)院耳鼻咽喉頭頸科住院患者常見致病菌及耐藥性,并探討其防治措施,為臨床治療提供依據(jù)。方法對醫(yī)院2014年1月-2016年12月耳鼻咽喉頭頸外科住院患者臨床標(biāo)本的病原菌鑒定結(jié)果及藥物敏感性試驗(yàn)結(jié)果進(jìn)行統(tǒng)計(jì)分析,并對其防治作初步探討。結(jié)果 19 588例患者中,248例有病原菌鑒定結(jié)果,其中革蘭陽性菌占39.1%,革蘭陰性菌占35.1%,真菌占12.5%,混合感染13.3%,其中單一病原中以銅綠假單胞菌檢出最多44株占17.7%,金黃色葡萄球菌次之,31株占12.5%,曲霉菌12株占4.8%;金黃色葡萄球菌對喹諾酮類抗菌藥物耐藥率為20.6%,銅綠假單胞菌對喹諾酮類抗菌藥物耐藥率達(dá)31.7%。結(jié)論耳鼻咽喉科使用抗菌藥物應(yīng)以臨床調(diào)查為依據(jù),覆蓋臨床常見致病菌,真菌感染在耳部病原中占重要地位,長時(shí)間應(yīng)用同類抗菌藥物易導(dǎo)致耐藥,應(yīng)適當(dāng)輪換抗菌藥物種類。
[Abstract]:Objective to investigate the common pathogenic bacteria and drug resistance in patients with head and neck department of otolaryngology in hospital, and to explore the preventive and therapeutic measures to provide evidence for clinical treatment. Methods from January 2014 to December 2016, the results of pathogenic bacteria identification and drug sensitivity test in clinical specimens of inpatients with otolaryngology and head and neck surgery in our hospital were statistically analyzed, and their prevention and treatment were preliminarily discussed. Results 248 of 19 588 patients were identified with pathogenic bacteria. Among them, Gram-positive bacteria accounted for 39.1%, Gram-negative bacteria 35.1m, fungi 12.5%, mixed infection was 13.30.Among the single pathogen, 44 strains were detected by Pseudomonas aeruginosa, 31 strains by Staphylococcus aureus accounted for 12.5strain, and 12 strains by Aspergillus aureus accounted for 4.8xu.among them, 44 strains were detected by Pseudomonas aeruginosa, 12.5strains by Staphylococcus aureus, 12 strains by Aspergillus aureus. The resistance rate of Staphylococcus to quinolones and Pseudomonas aeruginosa to quinolones was 20.6% and 31.775% respectively. Conclusion the use of antimicrobial agents in otorhinolaryngology should be based on the clinical investigation and cover the common clinical pathogenic bacteria. Fungal infection plays an important role in the etiology of the ear, and the use of the same antibiotics for a long time may lead to drug resistance. Types of antimicrobial agents should be rotated appropriately.
【作者單位】： 解放軍總醫(yī)院耳鼻咽喉頭頸外科;
【分類號】：R446.5;R76

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