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脈沖視野的短期波動(dòng)及其影響因素的研究

發(fā)布時(shí)間:2018-08-15 17:28
【摘要】:目的:運(yùn)用OCTOPUS 600全自動(dòng)電腦視野計(jì)觀察脈沖視野的短期波動(dòng)情況以及白內(nèi)障、年齡因素對(duì)脈沖視野測(cè)試結(jié)果的影響。方法:所有入選者分為兩組:正常組和白內(nèi)障組。正常組參與者是由青島大學(xué)附屬醫(yī)院黃島分院的職工、研究生及志愿者組成,共48例(48只眼),參與時(shí)間為2015年7月至2016年7月,所有入選的正常組參與者均于一周內(nèi)的不同一天,分別進(jìn)行一次脈沖視野測(cè)試,共三次,用時(shí)三天時(shí)間,分析這三次脈沖視野測(cè)試結(jié)果的平均敏感度(MS)、平均缺損(MD)及測(cè)試時(shí)間(t)有無(wú)差異,采用單因素方差分析進(jìn)行統(tǒng)計(jì)學(xué)檢驗(yàn),P0.05有統(tǒng)計(jì)學(xué)意義。按照年齡因素,將正常組參與者分為三個(gè)年齡組:(30歲)組、(30-40歲)組、(40歲)組,觀察年齡因素對(duì)第一次脈沖視野測(cè)試結(jié)果的平均敏感度(MS)、平均缺損(MD)及測(cè)試時(shí)間(t)的影響,采用線性回歸分析進(jìn)行統(tǒng)計(jì)學(xué)檢驗(yàn),P0.05有統(tǒng)計(jì)學(xué)意義。白內(nèi)障組的入選者是由2015年7月至2016年7月期間于青島大學(xué)附屬醫(yī)院黃島分院眼科就診的需行白內(nèi)障超聲乳化摘除聯(lián)合人工晶體植入手術(shù)的患者組成,共26例(32只眼),所有入選的白內(nèi)障患者分別于白內(nèi)障術(shù)前和術(shù)后第12天進(jìn)行一次脈沖視野測(cè)試,分析白內(nèi)障手術(shù)前后兩次脈沖視野測(cè)試結(jié)果的平均敏感度(MS)、平均缺損(MD)及測(cè)試時(shí)間(t)的變化,采用配對(duì)t檢驗(yàn)進(jìn)行統(tǒng)計(jì)學(xué)分析,P0.05有統(tǒng)計(jì)學(xué)意義。結(jié)果:在正常組中三次脈沖視野測(cè)試的MS值、MD值未見明顯變化,P(MS)=0.706,P(MD)=0.733,兩者均無(wú)統(tǒng)計(jì)學(xué)意義;而三次脈沖視野檢查的測(cè)試時(shí)間是縮短的,P(測(cè)試時(shí)間)=0.008,有統(tǒng)計(jì)學(xué)意義;在第一次脈沖視野測(cè)試中,年齡因素與脈沖視野測(cè)試的MS值、MD值和測(cè)試時(shí)間之間均無(wú)明顯關(guān)系,P(MS)=0.072,P(MD)=0.165,p(測(cè)試時(shí)間)=0.626,均無(wú)統(tǒng)計(jì)學(xué)意義。在白內(nèi)障患者組中,白內(nèi)障術(shù)后的MS值較術(shù)前顯著提高,P0.01,有顯著統(tǒng)計(jì)學(xué)意義;白內(nèi)障術(shù)后的MD值較術(shù)前顯著降低,P0.01,有顯著統(tǒng)計(jì)學(xué)意義;白內(nèi)障術(shù)后脈沖視野的測(cè)試時(shí)間較術(shù)前明顯縮短,P0.01,有顯著統(tǒng)計(jì)學(xué)意義。在所有入選者的脈沖視野測(cè)試結(jié)果中,MD值隨著MS值的升高而降低。結(jié)論:正常組中脈沖視野的短期波動(dòng)不明顯,隨著脈沖視野測(cè)試次數(shù)的增加,測(cè)試時(shí)間可能會(huì)縮短,白內(nèi)障因素對(duì)脈沖視野的測(cè)試結(jié)果影響較顯著,而年齡因素對(duì)脈沖視野的測(cè)試結(jié)果無(wú)明顯影響。
[Abstract]:Aim: to observe the short term fluctuation of pulsed visual field and the effect of age and cataract on the results of pulsed visual field test with OCTOPUS 600 automatic computerized visual field meter. Methods: all the selected patients were divided into two groups: normal group and cataract group. The participants in the normal group were workers, graduate students and volunteers from Huangdao Branch, affiliated Hospital of Qingdao University. There were 48 patients (48 eyes) who participated in the study from July 2015 to July 2016. All participants in the normal group underwent a pulse field test on different days of the week, three times a total of three times, for three days. Analysis of the three pulse field test results of the average sensitivity (MS), average defect (MD) and test time (t) there were differences in the use of univariate ANOVA statistical test (P0.05) had statistical significance. According to the age factors, the normal subjects were divided into three age groups: (30), (30-40), (40) years old. The influence of age factors on the average sensitivity (MS),) of the first pulsed visual field test (PFT) and the test time (t) were observed. Linear regression analysis was used for statistical test (P0.05). The cataract group was selected by patients who needed phacoemulsification and intraocular lens implantation from July 2015 to July 2016 at the Huangdao Branch of Qingdao University Hospital. A total of 26 patients (32 eyes) with cataract underwent a pulse field test before and 12 days after cataract. Before and after cataract surgery, the mean sensitivity of the results of twice pulse field test (MS),) and the change of test time (t) were analyzed. The paired t test was used for statistical analysis (P0.05). Results: in the normal group, there was no significant change in the MS value and MD value of the three pulse visual field tests (P (MS) = 0.706 and P (MD) = 0.733), and there was no significant difference between the two groups, but the test time of the third pulse visual field test was shortened to 0.008, which was statistically significant. In the first pulse field test, there was no significant correlation between age factor and MS value, MD value and test time. There was no significant difference between P (MS) 0.072 P (MD) 0.165 p (test time) and 0.626 (test time). In the cataract group, the MS value after cataract operation was significantly higher than that before cataract (P 0.01), and the MD value after cataract surgery was significantly lower than that before cataract surgery (P 0.01). The test time of pulse visual field after cataract surgery was significantly shorter than that before operation (P 0.01). The MD value decreased with the increase of MS value. Conclusion: the short-term fluctuation of pulsed visual field is not obvious in normal group. With the increase of pulse field test times, the test time may be shortened. Cataract factors have a significant effect on the results of pulsed visual field test. However, age had no significant effect on the results of pulsed visual field.
【學(xué)位授予單位】:青島大學(xué)
【學(xué)位級(jí)別】:碩士
【學(xué)位授予年份】:2017
【分類號(hào)】:R779.66

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