本文選題：阻塞性呼吸睡眠暫停/低通氣綜合征 + 肥胖��； 參考：《現(xiàn)代生物醫(yī)學(xué)進(jìn)展》2016年24期

【摘要】：目的:探討兒童阻塞性睡眠呼吸暫停/低通氣綜合征(OSAHS)與肥胖的相關(guān)性。方法:收集單純性肥胖兒童120例和體重正常兒童110例作為研究對(duì)象,進(jìn)行統(tǒng)一的體格檢查和專科檢查,并進(jìn)行多導(dǎo)睡眠監(jiān)測(cè)記錄阻塞性呼吸暫停指數(shù)(OAI)、呼吸暫停/低通氣指數(shù)(AHI)、中樞性呼吸暫停指數(shù)(CAI)、最低血氧飽和度(LSa O2)和睡眠效率。結(jié)果:肥胖組OSAHS患病率為58.33%顯著高于對(duì)照組的31.82%,差異有統(tǒng)計(jì)學(xué)意義(P0.05);OAI、AHI、CAI均顯著高于對(duì)照組,而LSa O2、睡眠效率指標(biāo)顯著低于對(duì)照組,差異均有統(tǒng)計(jì)學(xué)意義(均P0.05);多因素回歸分析顯示,肥胖、扁桃體增生、腺樣體增生是導(dǎo)致OSAHS的獨(dú)立危險(xiǎn)因素,差異有統(tǒng)計(jì)學(xué)意義(均P0.05)。結(jié)論:肥胖是兒童OSAHS發(fā)病的重要影響因素,特別是合并扁桃體腫大或腺樣體腫大的患兒應(yīng)注意預(yù)防OSAHS的發(fā)生。
[Abstract]:Objective: to investigate the relationship between obstructive sleep apnea / hypopnea syndrome (OSAHS) and obesity. Methods: 120 children with simple obesity and 110 children with normal body weight were collected as study subjects. The obstructive apnea index (OAI), apnea / hypopnea index (AHI), central apnea index (CAI), minimum oxygen saturation (LSAO _ 2) and sleep efficiency were recorded by polysomnography. Results: the prevalence rate of OSAHS in obesity group was 58.33%, significantly higher than that in control group (31.822%). The difference was statistically significant (P0.05). Multivariate regression analysis showed that obesity, tonsil hyperplasia and adenoid hyperplasia were independent risk factors for OSAHS (P0.05). Conclusion: obesity is an important factor in the pathogenesis of OSAHS in children, especially in children with tonsillar enlargement or adenoidomegaly should be paid attention to prevent the occurrence of OSAHS.
【作者單位】： 新疆醫(yī)科大學(xué)第一附屬醫(yī)院兒科;烏魯木齊兒童醫(yī)院風(fēng)濕免疫科;烏魯木齊兒童醫(yī)院耳鼻喉科;
【分類號(hào)】：R766;R723.14

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