良性陣發(fā)性位置性眩暈的前庭誘發(fā)肌源電位和前庭雙溫交替試驗(yàn)特性研究
本文選題:良性陣發(fā)性位置性眩暈 + 前庭功能; 參考:《福建醫(yī)科大學(xué)》2012年碩士論文
【摘要】:目的: 1.研究cVEMP oVEMP和BT的檢測(cè)方法和反應(yīng)特性,探討正常人群的cVEMP、oVEMP和BT是否受性別、年齡和耳間差異的影響; 2.研究BPPV患者的cVEMP、oVEMP和BT的反應(yīng)特性,,并通過(guò)與正常人群的各項(xiàng)檢測(cè)數(shù)據(jù)的對(duì)比,探討cVEMP、oVEMP和BT變化對(duì)眩暈定位診斷和預(yù)后評(píng)估的意義。 方法: 對(duì)64例正常人按不同性別、不同年齡和不同耳別分別進(jìn)行cVEMP、oVEMP和BT檢測(cè)。對(duì)33例BPPV患者患耳的cVEMP oVEMP和BT檢測(cè)數(shù)據(jù)分別與健耳和正常人群耳的檢測(cè)數(shù)據(jù)進(jìn)行對(duì)比,分析比較不同組別之間各項(xiàng)檢測(cè)數(shù)據(jù)的差異。 結(jié)果: 1.正常人群組不同性別、左右耳間cVEMP、oVEMP和BT試驗(yàn)的各項(xiàng)檢測(cè)數(shù)據(jù)無(wú)顯著性差異,不同年齡段cVEMP、oVEMP的潛伏期和BT的SPV無(wú)顯著性差異,但不同年齡段cVEMP、oVEMP的峰-峰振幅差異有顯著性意義。 2.病例組患耳的cVEMP、oVEMP各項(xiàng)檢測(cè)數(shù)據(jù)與正常人群耳對(duì)比,差別有顯著性意義。但兩組間BT的SPV無(wú)顯著性差異。 3.病例組患耳和健耳的cVEMP、oVEMP各項(xiàng)檢測(cè)數(shù)據(jù)對(duì)比差異有顯著性意義,但兩組間BT的SPV無(wú)顯著性差異。 4.病例組患耳的cVEMP、oVEMP異常率分別達(dá)到33%和36%,CP陽(yáng)性率達(dá)到48%。 結(jié)論: 1.正常人群不同年齡段峰-峰振幅差異有顯著性意義,年齡與振幅呈負(fù)相關(guān),說(shuō)明振幅隨年齡的增長(zhǎng)而降低。 2.病例組患耳的cVEMP、oVEMP各項(xiàng)檢測(cè)數(shù)據(jù)與健耳和正常人群耳的檢測(cè)數(shù)據(jù)對(duì)比差異有顯著性意義,但不同組間BT的SPV無(wú)顯著性差異。病例組患耳的cVEMP、oVEMP異常率分別達(dá)到33%和36%,CP陽(yáng)性率達(dá)到48%。說(shuō)明cVEMP、oVEMP和BT可以作為BPPV前庭功能狀態(tài)的客觀量化評(píng)估指標(biāo)。 3.對(duì)BPPV患者進(jìn)行cVEMP、oVEMP和BT檢測(cè)的結(jié)果表明對(duì)前庭球囊、橢圓囊和半規(guī)管的病理狀態(tài)和功能變化可以獲得客觀評(píng)價(jià)數(shù)據(jù),提示上述三項(xiàng)檢查方法對(duì)眩暈患者的定位診斷有一定的臨床價(jià)值,進(jìn)而可為眩暈治療的療效和預(yù)后判斷提供客觀依據(jù)。
[Abstract]:Objective: 1. To study the detection methods and response characteristics of cVEMP oVEMP and BT, and to investigate whether cVEMPOVEMP and BT are affected by sex, age and ear difference in normal population. 2. To study the response characteristics of cVEMPoVEMP and BT in patients with BPPV. The significance of the changes of cVEMPO VEMP and BT in the diagnosis and prognosis of vertigo was discussed. Methods: 64 normal subjects were tested for cVEMPoVEMP and BT according to sex, age and ear type. The data of camp oVEMP and BT in 33 patients with BPPV were compared with those of healthy ears and normal ears, and the differences among different groups were analyzed. Results: 1. There was no significant difference in the detection data between right and left ears of cVEMPOVEMP and BT test, but there was no significant difference in latency of camp and SPV between different age groups. 2. However, there were significant differences in peak to peak amplitudes of cVEMPG oVEMP in different age groups. 2. There was significant difference between the data of cVEMP and oVEMP in patients with different age groups compared with that of normal subjects. However, there was no significant difference in SPV between the two groups. 3. There was significant difference in the detection data of cVEMPOVEMP between the affected ears and healthy ears. However, there was no significant difference in SPV between the two groups. 4. The abnormal rate of cVEMPOVEMP in the affected ears reached 33% and 36% respectively. Conclusion: 1. There was significant difference between peak amplitude and peak amplitude in different age groups in normal population, and age was negatively correlated with amplitude. 2. The amplitude decreased with the increase of age. 2. There was a significant difference between the measured data of cVEMPOVEMP and that of healthy and normal ears, but there was no significant difference in SPV of BT between different groups. The abnormal rates of cVEMPOVEMP in the affected ears were 33% and 36%, respectively. It shows that cVEMPOVEMP and BT can be used as objective quantitative evaluation indexes of vestibular function status of BPPV. The results of cVEMPOVEMP and BT in BPPV patients showed that the pathological state and function of vestibular balloon, elliptical sac and semicircular canal could be evaluated objectively. The results suggest that the above three methods have certain clinical value in the localization diagnosis of vertigo patients, and can provide objective basis for the treatment of vertigo and the judgment of prognosis.
【學(xué)位授予單位】:福建醫(yī)科大學(xué)
【學(xué)位級(jí)別】:碩士
【學(xué)位授予年份】:2012
【分類號(hào)】:R764.3
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