本文選題：耳鼻喉 + 感染��； 參考：《中華醫(yī)院感染學(xué)雜志》2017年02期

【摘要】：目的研究耳鼻喉術(shù)后并發(fā)感染患者的血清炎癥因子、T淋巴細(xì)胞亞群等臨床指標(biāo)的表達(dá)水平和臨床意義,為耳鼻喉術(shù)后并發(fā)感染的臨床診治提供依據(jù)。方法選取2013年12月-2014年12月醫(yī)院收治的耳鼻喉手術(shù)患者68例,根據(jù)患者術(shù)后是否并發(fā)感染分成了感染組和非感染組,各34例,對(duì)兩組患者的C-反應(yīng)蛋白(CRP)、白介素-8(IL-8)、白介素-6(IL-6)、腫瘤壞死因子-α(TNF-α)和CD3+、CD4+、NK細(xì)胞百分比以及住院時(shí)間和抗菌藥物使用時(shí)間進(jìn)行觀察和比較。結(jié)果感染組患者的CRP、IL-8、IL-6、TNF-α分別為(18.73±4.32)mg/L、(33.87±3.28)ng/ml、(30.28±4.32)ng/ml、(5.87±1.38)ng/ml,高于非感染組的(8.92±2.18)mg/L、(20.86±3.19)ng/ml、(15.97±2.39)ng/ml、(1.83±0.63)ng/ml;感染組患者的CD3+、CD4+、NK細(xì)胞百分比分別為(47.83±5.34)%、(39.28±5.43)%、(20.35±6.54)%,低于非感染組的(57.42±7.34)%、(48.34±7.53)%、(38.27±8.01)%;感染組患者的住院時(shí)間和抗菌藥物使用時(shí)間分別為(10.83±1.81)d和(8.81±1.21)d,高于非感染組的(7.18±1.61)d和(5.19±1.02)d,差異均有統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論術(shù)后并發(fā)感染可導(dǎo)致耳鼻喉手術(shù)患者血清炎癥因子水平的升高和T淋巴細(xì)胞亞群相關(guān)指標(biāo)的降低,不利于患者術(shù)后恢復(fù),針對(duì)耳鼻喉術(shù)后感染實(shí)施有針對(duì)性的預(yù)防和干預(yù)具有重要的臨床意義。
[Abstract]:Objective to study the expression level and clinical significance of serum inflammatory factor T lymphocyte subsets in patients complicated with infection after otolaryngectomy, so as to provide basis for clinical diagnosis and treatment of infection after otolaryngectomy. Methods Sixty-eight patients undergoing otolaryngectomy were selected from December 2013 to December 2014. According to whether the patients were complicated with infection after operation, they were divided into infection group and non-infection group, 34 cases each. The percentage of C- reactive protein (CRP), interleukin-8 (IL-8), interleukin-6 (IL-6), tumor necrosis factor- 偽 (TNF- 偽), CD3 + CD4 ~ + NK cells, and the duration of hospitalization and antibiotic use were observed and compared between the two groups. 緇撴灉鎰熸煋緇勬?zhèn)ｈ�呯殑CRP,IL-8,IL-6,TNF-偽鍒嗗埆涓，

本文編號(hào)：2004650