本文選題：飛秒激光 + 準(zhǔn)分子激光原位角膜磨鑲術(shù)　； 參考：《國際眼科雜志》2016年03期

【摘要】：目的:觀察Keratograph眼表綜合分析儀檢查不同年齡組患者飛秒激光制瓣準(zhǔn)分子激光原位角膜磨鑲術(shù)(laser in situ keratomileusis,LASIK)術(shù)后淚膜的變化。方法:選擇性收集2014-07/2015-06在中山市人民醫(yī)院行飛秒激光制瓣LASIK的患者75例150眼,要求30歲以下、30~40歲、40歲以上患者各選取25例50眼。檢查術(shù)前,并隨訪術(shù)后1wk,1、2、3mo時患者的Keratograph眼表綜合分析儀檢查的淚膜破裂時間(tear break-up time,BUT)、淚河高度(tear meniscus height,TMH),并應(yīng)用Mc Monnies干眼病史問卷調(diào)查表(Mc Monnies Questionnaire,MQ)評估干眼癥狀得分。結(jié)果:三組患者術(shù)前干眼癥狀評分差異無統(tǒng)計學(xué)意義(P0.05),術(shù)后各時間點差異均有統(tǒng)計學(xué)意義(P0.05),均為30歲組最低,40歲以上組最高。術(shù)后1wk,三組干眼癥狀評分均較術(shù)前明顯上升,隨后均逐漸下降。其中,30歲以下、30~40歲組在術(shù)后2mo評分下降至術(shù)前水平,40歲以上組在術(shù)后3mo下降到術(shù)前水平。三組患者術(shù)前和術(shù)后各時點BUT和TMH差異均有統(tǒng)計學(xué)意義(P0.05),兩指標(biāo)均為30歲組最高,40歲以上組最低。術(shù)后1wk,三組患者兩指標(biāo)均較術(shù)前明顯下降,隨后均逐漸上升。其中,30歲以下、30~40歲組在術(shù)后3mo BUT回升至術(shù)前水平,而40歲以上組未回升到術(shù)前水平;30歲以下的TMH在術(shù)后2mo即回升到與基線沒有統(tǒng)計學(xué)差異,30~40歲組、40歲以上組的TMH在術(shù)后3mo回升到與基線沒有統(tǒng)計學(xué)差異。結(jié)論:飛秒激光制瓣LASIK術(shù)可影響干眼癥狀和淚膜的穩(wěn)定性,影響程度隨術(shù)后時間逐漸減弱,年齡越小的患者更快恢復(fù)至術(shù)前水平。
[Abstract]:Objective: to observe the changes of tear film after laser in situ keratomileusissis (LASIKA) in patients with femtosecond laser flap making excimer laser in situ keratomileusis (LASK) by Keratograph ocular surface comprehensive analyzer. Methods: 75 patients (150 eyes) who received femtosecond laser flap LASIK in Zhongshan people's Hospital in 2014-07 / 2015-06 were selected. 25 cases (50 eyes) of patients under 30 years old or over 40 years old were selected. The time of lacrimal film rupture was detected by Keratograph ocular surface comprehensive analyzer before operation and 1 week after operation. The tear film rupture time was tear break-up time, and the tear film height was higher than that of meniscus TMH. Mc Monnies dry eye history questionnaire and MC Monnies questionnaire were used to evaluate dry eye symptoms. Results: there was no significant difference in preoperative dry eye score among the three groups (P 0.05), but there was a significant difference at every time point after operation (P 0.05), which was the lowest in 30 years old group and the highest in more than 40 years old group. At 1 week after operation, the dry-eye symptom scores in all three groups increased significantly compared with those before operation, and then decreased gradually. The 2mo score decreased to the preoperative level in the group under 30 years old and the 3mo level decreased to the preoperative level in the group over 40 years old. There were significant differences in BUT and TMH between the three groups before and after operation (P 0.05). The two indexes were the highest in 30 years old group and the lowest in more than 40 years old group. At 1 wk after operation, the two indexes in the three groups were significantly lower than those before operation, and then increased gradually. In the group under 30 years old and 40 years old, the 3mo BUT level increased to the preoperative level after operation. However, the TMH of the group over 40 years old did not return to the preoperative level. The 2mo of the patients under 30 years of age increased to the baseline after operation. There was no significant difference between the TMH of the group of 30 and 40 years old and that of the group of over 40 years old. There was no statistical difference between the 3mo and the baseline after the operation. Conclusion: Femtosecond laser flap making LASIK can affect the stability of dry eye and tear film.
【作者單位】： 中國廣東省中山市人民醫(yī)院眼科;
【基金】：國家自然科學(xué)基金(No.81300731)~~
【分類號】：R779.63

【相似文獻(xiàn)】

相關(guān)期刊論文 前10條

1 曾原;黃一飛;高建華;;飛秒激光在角膜疾病中的應(yīng)用進(jìn)展[J];中國激光醫(yī)學(xué)雜志;2014年04期

2 ;飛秒激光治療老花眼[J];中國科技信息;2003年17期

3 高煦;李立;;飛秒激光在深板層內(nèi)皮角膜移植的應(yīng)用前景[J];國際眼科雜志;2007年06期

4 毛偉;周宏健;;飛秒激光在眼科領(lǐng)域中的應(yīng)用進(jìn)展[J];現(xiàn)代實用醫(yī)學(xué);2011年12期

5 黨光福;;飛秒激光在白內(nèi)障領(lǐng)域中的應(yīng)用[J];山東大學(xué)耳鼻喉眼學(xué)報;2011年05期

6 劉慧穎;周行濤;;飛秒激光輔助準(zhǔn)分子激光原位角膜磨鑲術(shù)后角膜內(nèi)皮細(xì)胞密度的臨床研究[J];中國眼耳鼻喉科雜志;2012年04期

7 彭昕;謝青;;飛秒激光在白內(nèi)障手術(shù)應(yīng)用進(jìn)展[J];中華臨床醫(yī)師雜志(電子版);2014年12期

8 陳迎月;黎新;;飛秒激光制瓣與準(zhǔn)分子激光磨鑲術(shù)治療角膜相對較薄的高度近視的療效比較[J];中國激光醫(yī)學(xué)雜志;2014年03期

9 夏毓;;飛秒激光在眼科手術(shù)中的應(yīng)用[J];中國激光醫(yī)學(xué)雜志;2007年04期

10 劉俐娜;陳曉蓮;鐘興武;陳海波;邢建強;丁輝;吳挺飛;;兩種飛秒激光制瓣LASIK術(shù)后的視覺質(zhì)量對比[J];眼科新進(jìn)展;2014年06期

相關(guān)重要報紙文章 前1條

1 本報記者 張永超;飛秒激光刀『飛』入中國內(nèi)地[N];醫(yī)藥經(jīng)濟報;2005年

，

本文編號：1943664