發(fā)布時間：2018-04-27 09:36

  本文選題：青年近視 + LASIK��； 參考：《眼科新進展》2017年08期

【摘要】：目的隨訪青年近視患者LASIK術(shù)后遠期干眼。方法以LASIK手術(shù)患者為治療組(A組),非手術(shù)單純近視患者為對照組(B組),分別于術(shù)前及術(shù)后1 a、3 a、5 a檢查患者裸眼視力、屈光度、淚膜破裂時間、角膜熒光素染色和淚液分泌試驗,診斷并填寫眼表疾病指數(shù)(ocular surface disease index,OSDI)調(diào)查問卷。結(jié)果A組術(shù)后干眼發(fā)病率高于術(shù)前(35.6%)且隨時間降低(術(shù)后1 a、3 a、5 a分別為51.7%、44.9%和40.7%),B組各時間點間差異無統(tǒng)計學意義(P0.05);兩組比較,術(shù)前差異無統(tǒng)計學意義(P0.05),術(shù)后其他時間A組均高于B組(均為P0.05)。A組術(shù)后輕度干眼占多數(shù)但逐年減少(分別為65.6%、52.8%和41.7%),中度和重度干眼構(gòu)成逐年提高,且重度干眼更為明顯(分別為6.6%、11.3%和16.7%;P0.05)。術(shù)后5 a,干眼患者裸眼視力和視覺功能OSDI評分均明顯低于非干眼患者(均為P0.05),殘留屈光度和眼部癥狀OSDI評分明顯高于非干眼患者(均為P0.05)。結(jié)論青年近視患者LASIK術(shù)后干眼長期存在甚至可能加重,要長期關注青年近視患者LASIK術(shù)后干眼進展。
[Abstract]:Objective to follow up the long-term dry eyes of young myopia patients after LASIK. Methods the patients with LASIK operation were used as the treatment group and the patients with non-surgical myopia as the control group. The naked eyesight, diopter and lacrimal film rupture time were examined before and after operation for 1 a, 3 a and 5 years, respectively. Corneal fluorescein staining and tear secretion test were used to diagnose and fill out the ocular surface disease index (OSDI) questionnaire. Results the incidence of dry eye in group A was higher than that in group A (35. 6% before operation) and decreased with time (51.7% 44.9% and 40.7% respectively) and there was no significant difference between two groups at different time points (P 0.05). There was no significant difference before operation (P 0.05), but the other time after operation in group A was higher than that in group B (both P0.05A group accounted for the majority but decreased year by year (65.6% and 41.7%, respectively). The composition of moderate and severe dry eyes increased year by year. The severe dry eyes were more obvious (6.6% and 16.7%, P 0.05%, respectively). 5 years after operation, the OSDI scores of naked eye and visual function in dry eye patients were significantly lower than those in non-dry eyes patients (P 0.05). The OSDI scores of residual diopter and ocular symptoms were significantly higher in dry eye patients than those in non-dry eyes patients (P 0.05). Conclusion the dry eye of young myopia patients may be aggravated after LASIK. It is necessary to pay attention to the progress of dry eye in young myopia patients after LASIK for a long time.
【作者單位】： 承德醫(yī)學院附屬醫(yī)院眼科;
【基金】：河北省科技支撐計劃項目(編號:20092084) 河北省自然科學基金面上項目(編號:H2015406054) 河北省政府資助省級臨床醫(yī)學優(yōu)秀人才項目(編號:361008)~~
【分類號】：R779.63

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