發(fā)布時(shí)間：2018-04-27 01:05

  本文選題：老年性白內(nèi)障 + 白內(nèi)障超聲乳化吸除并人工晶體植入術(shù)��； 參考：《大連醫(yī)科大學(xué)》2012年碩士論文

【摘要】：目的：通過第四代光學(xué)相干斷層掃描儀（Optical Coherence Tomography，OCT），對(duì)我院2011年1月至2011年7月間，，41例(41眼)行白內(nèi)障超聲乳化吸除術(shù)（Phacoemulsification，Phaco）的老年性白內(nèi)障患者黃斑中心凹與視盤周圍視網(wǎng)膜神經(jīng)纖維層（Retinal erve fiber layer,RNFL）厚度進(jìn)行測(cè)量，分析兩者術(shù)后變化規(guī)律，探討Phaco是否會(huì)引起眼底視神經(jīng)損傷。 方法：隨機(jī)選取2011年1月至2011年7月間于大連醫(yī)科大學(xué)附屬二院眼科行白內(nèi)障超聲乳化吸除并人工晶體植入術(shù)的老年性白內(nèi)障患者41例(41眼)。男21例(21眼)，女20例(20眼)。用OCT測(cè)量術(shù)前、術(shù)后1周、1個(gè)月、3個(gè)月、6個(gè)月的黃斑中心凹與視盤周圍視網(wǎng)膜神經(jīng)纖維層厚度的變化。 結(jié)果：術(shù)后1個(gè)月的黃斑區(qū)平均厚度與術(shù)前相比增加有統(tǒng)計(jì)學(xué)意義；而術(shù)后1周、術(shù)后3個(gè)月、術(shù)后6個(gè)月，黃斑區(qū)平均厚度值分別與術(shù)前相比差異無統(tǒng)計(jì)學(xué)意義；術(shù)后1個(gè)月和3個(gè)月視盤周邊部視網(wǎng)膜神經(jīng)纖維層厚度增加有統(tǒng)計(jì)學(xué)意義；而術(shù)后1周、術(shù)后6個(gè)月視盤周邊部視網(wǎng)膜神經(jīng)纖維層厚度值與術(shù)前相比差異無統(tǒng)計(jì)學(xué)意義；術(shù)后1個(gè)月黃斑中心凹厚度均值最大，而術(shù)后3個(gè)月時(shí)視盤周圍視網(wǎng)膜神經(jīng)纖維層厚度最大。 結(jié)論：老年性白內(nèi)障患者行phaco術(shù)后1個(gè)月黃斑平均厚度增加，3個(gè)月后恢復(fù)至術(shù)前水平；術(shù)后1個(gè)月至3個(gè)月視盤周圍平均RNFL厚度均增加，6個(gè)月后恢復(fù)至術(shù)前水平。說明phaco術(shù)后眼底視網(wǎng)膜雖有變化，但變化是短暫和可逆的。只要術(shù)前檢查完善、操作手法熟練、術(shù)后治療得當(dāng)，phaco不會(huì)引起嚴(yán)重的眼底視網(wǎng)膜并發(fā)癥。證實(shí)了phaco手術(shù)的安全性，為phaco手術(shù)的臨床發(fā)展提供了理論依據(jù)。
[Abstract]:Objective: to perform phacoemulsification in 41 cases (41 eyes) of senile cataract patients with macular fovea and perioptic disc by the fourth generation optical coherence tomography (OCTT) in our hospital from January 2011 to July 2011. The thickness of Retinal erve fiber layerus was measured. To investigate whether Phaco can cause fundus optic nerve injury. Methods: 41 patients (41 eyes) with senile cataract underwent phacoemulsification and intraocular lens implantation from January 2011 to July 2011 in the second affiliated Hospital of Dalian Medical University. There were 21 eyes of male and 20 of female. The thickness of macular fovea and retinal nerve fiber layer around optic disc was measured by OCT before operation, 1 week, 1 month, 3 months and 6 months after operation. Results: the mean thickness of macular area increased significantly at 1 month after operation compared with that before operation, but there was no significant difference in mean thickness of macular area between 1 week, 3 months and 6 months after operation. The thickness of the retinal nerve fiber layer around the disc increased significantly 1 and 3 months after the operation, but there was no significant difference in the thickness of the retinal nerve fiber layer around the disc at 1 week and 6 months after the operation. The mean thickness of macular fovea was the highest at 1 month after operation, and the thickness of retinal nerve fiber layer around optic disc was the largest at 3 months after operation. Conclusion: the mean macular thickness increased 1 month after phaco and recovered to the preoperative level after 3 months, and the mean RNFL thickness around the optic disc increased from 1 month to 3 months after phaco, and recovered to the preoperative level after 6 months. The results showed that the changes of retinal fundus after phaco were transient and reversible. So long as the preoperative examination is perfect and the operation is skillful, the proper treatment of phaco after operation will not cause serious retinal complications. The safety of phaco surgery is confirmed, which provides a theoretical basis for the clinical development of phaco surgery.
【學(xué)位授予單位】：大連醫(yī)科大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2012
【分類號(hào)】：R779.6

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