本文選題：角膜塑形鏡 + 玻璃酸鈉滴眼液��； 參考：《國(guó)際眼科雜志》2016年03期

【摘要】：目的:觀察1g/L玻璃酸鈉滴眼液(不含防腐劑)對(duì)青少年近視患者配戴硬性透氣性角膜接觸鏡(RGP)相關(guān)性干眼的療效評(píng)價(jià)。方法:選擇2015-01/05來(lái)我院門(mén)診就診的90例透氣性角膜接觸鏡相關(guān)性干眼癥近視患者,年齡12.75±4.15歲,屈光度-3.50±1.50D,患者均接受正規(guī)角膜塑形鏡驗(yàn)配。將患者隨機(jī)分為3組,每組30例60眼:A組使用RGP潤(rùn)滑液,4次/d,1滴/次;B組使用1g/L玻璃酸鈉滴眼液(不含防腐劑),4次/d,1滴/次;C組在使用RGP潤(rùn)滑液(4次/d,1滴/次)后15min再用1g/L玻璃酸鈉滴眼液(不含防腐劑)(4次/d,1滴/次)。觀察各組患者用藥前1d與用藥后第1、2、4wk的眼部癥狀評(píng)分、Schirmer I試驗(yàn)(SⅠt)、淚膜破裂時(shí)間(BUT)、角膜熒光染色評(píng)分變化。結(jié)果:三組患者在用藥1wk后的干眼癥狀、角膜熒光染色和BUT均較治療前有明顯的改善(PO.05),三組患者的SⅠt值治療前后差異均無(wú)統(tǒng)計(jì)學(xué)意義(P0.05)。各組患者在治療第2、4wk后和治療1wk時(shí)測(cè)得的各項(xiàng)指標(biāo)差異無(wú)統(tǒng)計(jì)學(xué)意義(P0.05)。B組與A組對(duì)干眼癥狀、SⅠt和BUT的改善作用差異無(wú)統(tǒng)計(jì)學(xué)意義(P0.05);B組較A組改善角膜熒光染色作用更明顯,差異有統(tǒng)計(jì)學(xué)意義(P0.05)。C組對(duì)改善干眼癥狀和角膜熒光染色作用優(yōu)于A組(PO.05)。C組對(duì)改善干眼癥狀上優(yōu)于B組(P0.05)。結(jié)論:1g/L玻璃酸鈉滴眼液(不含防腐劑)能夠穩(wěn)定淚膜,促進(jìn)角膜上皮損傷愈合,改善青少年近視患者配戴硬性透氣性角膜接觸鏡所致干眼癥狀,具有一定的臨床應(yīng)用價(jià)值。
[Abstract]:Objective: to evaluate the effect of 1g/L sodium hyaluronate eye drops (excluding preservatives) on dry eyes of juvenile myopia patients wearing rigid breathable contact lens. Methods: 90 patients with penetrating contact lens associated dry eye myopia, aged 12.75 鹵4.15 years and diopter -3.50 鹵1.50D, were selected from our outpatient clinic in 2015-01 / 05. The patients were randomly divided into three groups. Each group of 30 cases: 60 eyes: group A received RGP lubricant 4 times a drop per day, group B used 1g/L sodium hyaluronate eye drops (no preservatives 4 times per day per day), group C received 1g/L sodium hyaluronate after using RGP lubricating fluid for 4 times a drop per day. Eye fluid (not containing preservatives). The ocular symptom scores and the time of tear film rupture and corneal fluorescence staining were observed 1 day before and 2 weeks after treatment in each group. Schirmer I test was used to test S 鈪，

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