本文選題：干眼　切入點：瞼板腺功能障礙　出處：《眼科新進展》2017年12期

【摘要】：目的探討干眼的危險因素及發(fā)生頻率。方法 564例(564眼)納入研究,采用問卷調(diào)查的方式對研究對象干眼的癥狀、體征及全身情況進行評估。采用SPSS 16.0統(tǒng)計學(xué)軟件分析數(shù)據(jù),χ2和t檢驗進行組間差異分析,Logistic回歸分析危險因素和干眼的關(guān)系。結(jié)果口干與重癥干眼的癥狀(OR=2.89,95%CI:1.6~5.5,P=0.001)有相關(guān)性。使用胃潰瘍藥物加重重癥干眼的癥狀(OR=2.60,95%CI:1.1~5.1,P=0.04)。使用人工淚液加重重癥干眼體征(OR=2.1,95%CI:1.2~3.2,P=0.01)�？诟�(OR=1.92,95%CI:1.02~3.60,P=0.04)及使用利尿劑(OR=6.00,95%CI:1.3~41.0,P=0.02)均為淚液分泌障礙的危險因素。年齡較大(OR=1.02,95%CI:1.05~1.09,P=0.000)、男性(OR=1.42,95%CI:1.04~2.60,P=0.02)、關(guān)節(jié)炎(OR=8.00,95%CI:1.0~59.0,P=0.02)和使用降壓藥(OR=2.85,95%CI:1.3~5.7,P=0.01)為瞼板腺功能障礙的危險因素。口干是角膜染色的危險因素(OR=2.21,95%CI:1.1-5.4,P=0.02)。結(jié)論不同的危險因素對干眼影響不同,表明干眼的不同亞型具有不同病理生理機制。
[Abstract]:Objective to investigate the risk factors and frequency of dry eye.Methods 564 cases (564 eyes) were included in the study. The symptoms, signs and systemic conditions of dry eyes were evaluated by questionnaire.SPSS 16.0 statistical software was used to analyze the data, 蠂 2 and t test were used to analyze the relationship between the risk factors and dry eyes by logistic regression analysis.Results there was a correlation between dry mouth and the symptoms of severe dry eye.The symptoms of severe dry eye were aggravated by gastric ulcer drugs.Artificial tear was used to aggravate the severe dry eye signs.The risk factors of tear secretion disorder were: I: 1.023.60P0.04) and the use of diuretics: 6.000.95 CI: 1.92P0.02).騫撮緞杈冨ぇ(OR=1.02,95%CI:1.05~1.09,P=0.000),鐢鋒，

本文編號：1704491