本文選題：馬凡綜合征　切入點：角膜曲率　出處：《眼科新進展》2017年11期 　論文類型：期刊論文

【摘要】：目的比較不同年齡段馬凡綜合征晶狀體不全脫位患者的角膜特征并探討其臨床意義。方法馬凡綜合征組45例84眼和對照組84例84眼列入研究,前者按年齡分為兩組:兒童組(5~14歲)49眼和非兒童組(14歲)35眼。使用Pentacam測量角膜曲率、角膜散光和中央角膜厚度。結果與對照組相比,馬凡綜合征組患者角膜變平、散光增大,兩組間差異均具有統(tǒng)計學意義(均為P=0.000)。馬凡綜合征患者角膜前表面曲率兒童組為(40.02±1.42)D,非兒童組為(41.03±1.57)D;角膜后表面曲率兒童組為(-5.71±0.23)D,非兒童組為(-5.89±0.31)D;總角膜散光兒童組為(-1.71±0.84)D,非兒童組為(-1.34±0.78)D,兩組相比差異均具有統(tǒng)計學意義(均為P0.05)。角膜前表面散光兒童組高于非兒童組(P=0.017),而后表面散光兩組間差異無統(tǒng)計學意義(P=0.377)。兒童組總角膜散光和角膜前表面散光以順規(guī)散光(69.39%)為主,而非兒童組順規(guī)散光和斜向散光的比例相當。兩組角膜后表面都以逆規(guī)散光為主(兒童組占85.71%,非兒童組占77.14%)。以角膜前表面散光估計總角膜散光時約有一半的患者會高估約0.32 D。結論馬凡綜合征晶狀體不全脫位患者角膜變平、散光增大。兒童組角膜更扁平,總角膜散光和角膜前表面散光值較高,以順規(guī)散光為主。馬凡綜合征患者的角膜后表面散光值較穩(wěn)定,以逆規(guī)散光為主。忽視角膜后表面散光,以角膜前表面散光值估計總角膜散光時易高估。
[Abstract]:Objective to compare the corneal features and clinical significance of patients with Marfan syndrome with incomplete dislocation of lens in different age groups. Methods 45 cases (84 eyes) of Marfan syndrome group and 84 eyes of 84 cases (control group) were included in the study. Pentacam was used to measure corneal curvature, astigmatism and central corneal thickness. Results compared with the control group, the cornea flattened and astigmatism increased in the Marfan syndrome group. There were significant differences between the two groups (P < 0.000). The anterior surface curvature of cornea was 40.02 鹵1.42D in children with Marfan syndrome, 41.03 鹵1.57D in non-children, -5.71 鹵0.23D in children with corneal posterior surface curvature, -5.89 鹵0.31D in non-children, and -1.71 鹵0.84D in children with total corneal astigmatism. The difference between the two groups was statistically significant (P 0.05). The anterior corneal surface astigmatism in children group was higher than that in non-children group (P 0.017), but there was no significant difference between the two groups in posterior surface astigmatism. The total corneal astigmatism and corneal astigmatism in children group were not significantly different. The main astigmatism of the front surface is in accordance with the rules of astigmatism (69.39). The proportion of normal astigmatism and oblique astigmatism was the same in non-children group. The posterior surface of cornea in both groups was mainly converse astigmatism (85.71 in children group, 77.14 in non-child group). About half of the patients estimated total corneal astigmatism by anterior corneal surface astigmatism. Conclusion the cornea flattened in patients with Marfan's syndrome with incomplete lens dislocation. The corneal astigmatism in the children group was more flat, the total corneal astigmatism and the corneal anterior surface astigmatism were higher, the main astigmatism was regular astigmatism. In the patients with Marfan's syndrome, the astigmatism value of the posterior surface of cornea was more stable, the main astigmatism was reverse astigmatism, and the corneal posterior surface astigmatism was ignored. It is easy to overestimate the total corneal astigmatism based on the corneal anterior surface astigmatism.
【作者單位】： 復旦大學附屬眼耳鼻喉科醫(yī)院眼科;維吾爾族自治區(qū)喀什地區(qū)第二人民醫(yī)院眼科;
【基金】：國家自然科學基金聯(lián)合基金資助(編號:U1503124) 新疆維吾爾自治區(qū)自然科學基金資助(編號:2015211C225)~~
【分類號】：R776.2

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