本文選題：正視化　切入點(diǎn)：眼軸　出處：《昆明醫(yī)科大學(xué)》2012年碩士論文　論文類型：學(xué)位論文

【摘要】：目的：探討不同實(shí)驗(yàn)室光照環(huán)境(全光譜燈、日光燈、自然光)對(duì)嬰幼兒恒河猴正視化過程的影響。 方法：八只平均年齡為100天(95天-105天)的嬰幼兒恒河猴,被隨機(jī)分為全光譜燈組、日光燈組和自然光組三組。光照之前及光照后的第二、四、六、八、十二周時(shí)重復(fù)測(cè)量眼球生物學(xué)參數(shù)(包括眼軸長(zhǎng)度、前房深度、晶體厚度、玻璃體腔長(zhǎng)度、角膜曲率、屈光度六個(gè)參數(shù)),用以觀察各時(shí)間點(diǎn)各組各個(gè)參數(shù)之間是否存在統(tǒng)計(jì)學(xué)差異,并觀察各組各參數(shù)的變化趨勢(shì)。各個(gè)時(shí)間點(diǎn)的數(shù)據(jù)采用重復(fù)測(cè)量數(shù)據(jù)的方差分析,以P0.05為有統(tǒng)計(jì)學(xué)意義。 結(jié)果：光照前后各時(shí)間點(diǎn)各組六個(gè)參數(shù)之間均無統(tǒng)計(jì)學(xué)差異。日光燈組增速較其他兩組快,而以第六周和第十二周增速最快。在第八周時(shí),三組恒河猴的晶體厚度下降速度均減緩,但各組間無統(tǒng)計(jì)學(xué)差異(P0.05),之后下降速度增大至下降前水平。光照后,第四周時(shí)日光燈組恒河猴角膜曲率輕微上升,之后繼續(xù)下降,十二周是增幅明顯：第八周時(shí)全光譜燈組恒河猴角膜曲率增幅明顯,之后繼續(xù)下降；而自然光組角膜曲率一直在下降,降速亦無明顯改變。 結(jié)論：全光譜燈、日光燈、自然光作為照明光源,三種不同實(shí)驗(yàn)室光照環(huán)境對(duì)嬰幼兒恒河猴正視化過程的影響無顯著差異。
[Abstract]:Objective: to investigate the effects of different laboratory light environment (full spectrum lamp, fluorescent lamp, natural light) on the emmetrization process of infant rhesus monkey (Rhesus mulatta). Methods: eight rhesus monkeys with an average age of 100 days (95 days to 105 days) were randomly divided into three groups: the full spectrum lamp group, the fluorescent lamp group and the natural light group. At 12 weeks, the biological parameters of eyeball (including axial length, anterior chamber depth, lens thickness, length of vitreous cavity, corneal curvature) were measured repeatedly. The diopter is used to observe whether there is statistical difference between the parameters of each group at each time point, and to observe the change trend of each parameter. The data of each time point are analyzed by the analysis of variance of the repeated measurement data. In order to P0.05 for statistical significance. Results: there was no statistical difference between the six parameters at each time point before and after illumination. The growth rate of the fluorescent lamp group was faster than that of the other two groups, but the fastest growth rate was at 6th weeks and 12th weeks. At 8th weeks, The decrease rate of lens thickness in the three groups slowed down, but there was no significant difference between the three groups (P 0.05), but the decrease rate increased to the level before the decrease. After light exposure, the corneal curvature of the rhesus monkeys in the fluorescent lamp group increased slightly at the fourth week, and then continued to decrease. At 12 weeks, the corneal curvature of the rhesus monkey increased significantly at 8th weeks, but the corneal curvature of the natural light group continued to decrease, and the speed of the decrease did not change significantly in the natural light group. Conclusion: there is no significant difference in the emitulization process of infant rhesus monkey under three different laboratory illumination conditions: full spectrum lamp, fluorescent lamp and natural light.
【學(xué)位授予單位】：昆明醫(yī)科大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2012
【分類號(hào)】：R778.1

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