本文關(guān)鍵詞：降鈣素原及白介素-6測(cè)定在急性扁桃體炎合并膿毒癥患兒中的診斷價(jià)值研究　出處：《中華醫(yī)院感染學(xué)雜志》2017年05期 　論文類型：期刊論文

  更多相關(guān)文章： 膿毒癥 急性扁桃體炎 降鈣素原 白介素- 診斷

【摘要】：目的研究降鈣素原及白介素-6測(cè)定在小兒急性扁桃體炎并膿毒癥患兒中的診斷價(jià)值。方法選取2013年6月-2015年7月急性扁桃體炎并膿毒癥患兒86例為膿毒癥組,急性扁桃體炎患兒90例為扁桃體炎組、健康兒童44例為對(duì)照組;分別對(duì)患兒進(jìn)行降鈣素原(PCT)、白介素-6(IL-6)、C-反應(yīng)蛋白(CRP)、白細(xì)胞計(jì)數(shù)(WBC)、中性粒細(xì)胞比值(N)水平以及急性生理與慢性健康狀況評(píng)分系統(tǒng)Ⅱ(APACHEⅡ)評(píng)分測(cè)定,比較其結(jié)果在三組中治療前、第3天、第5天及治療結(jié)束變化情況。結(jié)果治療前,膿毒癥組、扁桃體炎組PCT為(14.92±3.84)ng/mL、(11.10±1.00)ng/mL、IL-6為(365.20±78.00)ng/L、(262.20±47.00)ng/L)、CRP為(19.48±2.00)mg/L、(16.20±2.32)mg/L、WBC為(18.50±7.40)×109/L、(11.60±2.40)×109/L、N為(85.00±4.70)%、(78.00±2.15)%水平以及APACHEⅡ評(píng)分(20.60±4.20)分、(14.61±2.10)分,均高于對(duì)照組,差異有統(tǒng)計(jì)學(xué)意義(P0.05);膿毒癥組,治療第3天各項(xiàng)指標(biāo)(PCT(25.12±4.10)ng/mL、IL-6(468.20±64.00)ng/L、CRP(24.60±3.10)mg/L、WBC(22.72±2.10)×109/L、N(89.00±3.84)%水平以及APACHEⅡ評(píng)分(27.10±3.10)分,均高于治療前;治療第5天(PCT(13.05±2.16)ng/mL、IL-6(80.50±4.10)ng/L、CRP(14.20±3.30)mg/L、WBC(7.20±1.00)×109/L、N(89.00±3.84)%水平以及APACHEⅡ評(píng)分(14.20±3.30)分,低于治療第3天;治療第3天和第5天,各項(xiàng)指標(biāo)高于扁桃體炎組,差異有統(tǒng)計(jì)學(xué)意義(P0.05);治療結(jié)束,與扁桃體炎組比較,差異無統(tǒng)計(jì)學(xué)意義。結(jié)論 PCT及IL-6檢測(cè)有助于小兒急性扁桃體炎合并膿毒癥的早期診斷、病情評(píng)估和臨床指導(dǎo),且PCT、IL-6的截?cái)嘀?4.50ng/mL、365.50ng/L,能為臨床早期診斷提供參考。
[Abstract]:Objective to study the diagnostic value of procalcitonin and interleukin-6 in children with acute tonsillitis and sepsis. Methods Children with acute tonsillitis complicated with sepsis from June 2013 to July 2015 were selected. 6 cases were sepsis group. 90 children with acute tonsillitis were in tonsillitis group and 44 healthy children as control group. The patients were treated with procalcitonin proto-PCT, interleukin-6 / IL-6 / C-reactive protein (CRP) and white blood cell count (WBC) respectively. The level of neutrophil / neutrophil ratio and the acute physiological and chronic health status scoring system 鈪，

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