本文關鍵詞：滄州市39356例新生兒聽力篩查結果分析　出處：《聽力學及言語疾病雜志》2016年01期 　論文類型：期刊論文

  更多相關文章： 新生兒 聽力篩查 聽力損失 基因

【摘要】：目的了解滄州市新生兒聽力篩查狀況。方法應用DPOAE對滄州市2013~2014年出生新生兒(不包括高危兒)進行聽力篩查,初篩未通過者42天進行復篩,復篩未通過者3個月進行聽力診斷,對于診斷聽力損失者進行GJB2、GJB3、SLC26A4、mtDNA 12SrRNA四個常見耳聾基因突變篩查。結果滄州市2013~2014年共出生新生兒44 456例,完成初篩的新生兒為39 356例(88.53%,39 356/44 456),初篩未通過5 437例(13.81%,5 437/39 356),復篩2 153例(39.60%,2 153/5 437),復篩未通過215例(9.99%,215/2 153),轉診進行聽力診斷者71例(33.02%,71/215),確診聽力損失48例,其中單耳聽力損失20例中,輕度聽力損失13例,中度聽力損失5例,極重度聽力損失2例;雙耳聽力損失28例中,輕度-中度聽力損失18例,重度以上聽力損失10例,聽力損失檢出率1.22‰(48/39 356);這48例中,13例(27.08%,13/48)耳聾基因篩查陽性。結論滄州市2013~2014兩年新生兒聽力損失檢出率為1.22‰,復篩率和轉診率均較低。
[Abstract]:Objective to investigate the status of neonatal hearing screening in Cangzhou. Methods DPOAE was used to screen the hearing of newborns (excluding high-risk infants) born in Cangzhou from 2013 to 2014. The patients who had not passed the primary screening were screened again for 42 days, the patients who failed the screening were diagnosed by hearing for 3 months, and the patients with hearing loss were diagnosed with GJB _ 2, GJB _ 3 and SLC26A4. MtDNA 12s rRNA was screened for four common deafness gene mutations. Results 44,456 newborns were born in Cangzhou from 2013 to 2014. The total number of newborns who completed the primary screening was 39 356/44 456m (39 356 / 88.53), and the primary screening failed 5 437 cases (13.81%). 5 437/39 356m, 2153 cases of double sieve, 2 153/5 437m, 21515 / 2153). Among the 71 cases who were referred for hearing diagnosis, there were 71 cases (33.02%) diagnosed hearing loss, 48 cases were confirmed hearing loss, of which 20 cases were single ear hearing loss, 13 cases were mild hearing loss and 5 cases were moderate hearing loss. Very severe hearing loss in 2 cases; Among the 28 cases of binaural hearing loss, there were 18 cases of mild to moderate hearing loss and 10 cases of severe hearing loss. The detection rate of hearing loss was 1.22 鈥，

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