【摘要】：目的探討血清骨特異性堿性磷酸酶(BALP)、抗酒石酸酸性磷酸酶(TRAP-5b)及股骨近端骨小梁類型(Singh)指數(shù)在預(yù)測老年髖部骨折發(fā)生中的臨床應(yīng)用。方法老年髖部骨折患者50例為觀察組,并選擇同期體檢的健康老年人45例為對照組。分析血清BALP、TRAP-5b及Singh指數(shù)的差異及采用Pearson相關(guān)性檢驗(yàn)分析其相關(guān)性。結(jié)果觀察組Singh指數(shù)主要集中于3~4級,對照組主要集中在4~5級,兩組Singh指數(shù)分布的整體差異有統(tǒng)計(jì)學(xué)意義(P0.05)。觀察組血清BALP、TRAP-5b水平均明顯高于對照組,而Singh指數(shù)低于對照組(P0.05)。Pearson相關(guān)性分析顯示,BALP與TRAP-5b呈正相關(guān)(r=0.476,P0.05),BALP和TRAP-5b與Singh指數(shù)均呈負(fù)相關(guān)(r=-0.571、-0.488,P0.05)。BALP、TRAP-5b和Singh指數(shù)預(yù)測髖部骨折發(fā)生的敏感度分別為72.37%、59.20%和64.00%,三者聯(lián)合預(yù)測敏感度為93.50%。結(jié)論老年髖部骨折患者血清BALP、TRAP-5b水平升高,Singh指數(shù)降低,三者結(jié)合預(yù)測老年髖部骨折具有較高的敏感性,可作為老年髖部骨折風(fēng)險(xiǎn)預(yù)測的指標(biāo)。
[Abstract]:Objective to investigate the clinical application of serum bone-specific alkaline phosphatase (BALP),) anti-tartrate acid phosphatase (TRAP-5b) and proximal femurs type (Singh) index in predicting the occurrence of hip fracture in the elderly. Methods 50 elderly patients with hip fracture were selected as observation group and 45 healthy elderly as control group. The difference of serum BALP,TRAP-5b and Singh index was analyzed and the correlation was analyzed by Pearson correlation test. Results the Singh index was mainly concentrated in 3 鈮，

本文編號：2518565