系統(tǒng)康復(fù)訓(xùn)練配合神經(jīng)節(jié)苷脂對(duì)脊髓損傷患者生活自理能力及血清炎性因子水平的影響
[Abstract]:Objective to investigate the effects of systematic rehabilitation training combined with ganglioside on self-care ability and serum inflammatory factors in patients with spinal cord injury. Methods Seventy-eight patients with spinal cord injury were randomly divided into control group (n = 39) and observation group (n = 39). The control group was treated with routine systematic rehabilitation training, and the observation group was treated by intravenous infusion of tetrahexose monosialate ganglioside sodium on the basis of the control group. The treatment period was 30 days and the treatment period was 2 cycles. The activity of daily living (Barthel) scale, self rating anxiety scale (SAS) and self rating depression scale (SDS) were used to evaluate the ability of living and emotion before and after treatment. The serum levels of interleukin (IL) -8 and IL-1 尾 and tumor necrosis factor (TNF)-偽 were measured by enzyme linked immunosorbent assay (Elisa) before and after treatment. Results after treatment, the Barhel index in both groups was significantly higher than that in the control group (P0.05). After treatment, the SDS and SAS scores in the observation group were significantly lower than those in the control group (P0.05). After treatment, the contents of IL-8, IL-1 尾 and TNF- 偽 in the two groups were significantly lower than those in the control group (P0.05). The observation group was significantly lower than the control group (P0.05). Conclusion systematic rehabilitation training combined with ganglioside can effectively improve the self-care ability of daily life of patients with spinal cord injury, alleviate the negative emotion of depression and anxiety, and decrease the levels of IL-8, IL-1 尾 and TNF- 偽 in patients with spinal cord injury. The treatment of spinal cord injury patients has certain curative effect.
【作者單位】: 徐州市第一人民醫(yī)院骨科;
【基金】:江蘇大學(xué)2014年度醫(yī)學(xué)臨床科研發(fā)展基金項(xiàng)目(No.JLY20140125)
【分類號(hào)】:R651.2
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