脾與殘肝體積比和肝切除術(shù)后肝功能相關(guān)分析研究
發(fā)布時(shí)間:2018-07-05 15:11
本文選題:原發(fā)性肝癌 + 肝功能試驗(yàn)。 參考:《新疆醫(yī)科大學(xué)》2015年碩士論文
【摘要】:目的:研究探討脾與殘肝體積比在肝切除手術(shù)后的肝臟儲(chǔ)備功能的評(píng)估價(jià)值。應(yīng)用肝臟三維重建軟件IQQA-Liver(美國(guó)EDDA公司)和水侵法測(cè)量原發(fā)性肝癌肝切除術(shù)后殘肝體積、脾臟體積,并計(jì)算出脾與殘肝體積比,分析脾與殘肝體積比和肝癌切除術(shù)后肝功能指標(biāo)的相關(guān)性,了解脾與殘肝體積對(duì)術(shù)后肝臟儲(chǔ)備功能的影響,為臨床醫(yī)生在術(shù)前準(zhǔn)確評(píng)估術(shù)后肝臟功能,避免肝癌切除術(shù)后肝功能衰竭的發(fā)生提供指導(dǎo)。方法:回顧性分析2012年2月至2013年6月共57例被我科診斷為實(shí)施手術(shù)治療的肝硬化肝癌患者,應(yīng)用肝臟三維重建軟件IQQA-Liver和水侵法測(cè)量原發(fā)性肝癌肝切除術(shù)后殘肝體積、脾臟體積,并計(jì)算出脾與殘肝體積比,分析脾與殘肝體積比與患者術(shù)后肝功能情況及住院時(shí)間的關(guān)系。結(jié)果:經(jīng)過(guò)多元回歸分析結(jié)果提示肝癌肝切除術(shù)后肝功能評(píng)分Child-Pugh與脾與殘肝體積比有關(guān)。脾與殘肝體積比值越小。其評(píng)分越低(t=7.731,P≈0.000),即肝臟儲(chǔ)備功能越好。當(dāng)脾與殘肝體積比≤0.9時(shí);颊咧形蛔≡簳r(shí)間為13 d(11-15 d)。當(dāng)脾與殘肝體積比0.9時(shí),患者中位住院時(shí)間為21 d(14-28d)。兩者的住院時(shí)間差異有統(tǒng)計(jì)學(xué)意義(P=0.000)。結(jié)論:脾與殘肝體積比可以有效預(yù)測(cè)肝癌肝切除術(shù)后的肝臟儲(chǔ)備功能,術(shù)前應(yīng)制定詳細(xì)的手術(shù)計(jì)劃,估算殘肝體積(脾與殘肝體積比≤0.9),避免手術(shù)風(fēng)險(xiǎn),減少術(shù)后肝功能損害的發(fā)生。
[Abstract]:Objective: to investigate the value of spleen to residual liver volume ratio in evaluating liver reserve function after hepatectomy. The residual liver volume and spleen volume after hepatectomy were measured by using IQQA-Liver (EDDA company) and water invasion method, and the volume ratio of spleen to remnant liver was calculated. To analyze the correlation between the volume ratio of spleen and remnant liver and the liver function index after hepatectomy, to understand the effect of spleen and residual liver volume on liver reserve function after hepatectomy, so as to evaluate the liver function accurately before and after hepatectomy. To avoid liver failure after hepatectomy provides guidance. Methods: from February 2012 to June 2013, 57 patients with liver cirrhosis diagnosed by our department as surgical treatment were analyzed retrospectively. The residual liver volume after hepatectomy was measured by IQQA-Liver and water invasion software. The volume ratio of spleen to remnant liver was calculated and the relationship between the volume ratio of spleen and residual liver and postoperative liver function and hospitalization time was analyzed. Results: the results of multiple regression analysis showed that Child-Pugh was related to the volume ratio of spleen to remnant liver after hepatectomy. The smaller the volume ratio of spleen to remnant liver was. The lower the score (t = 7.731 P 鈮,
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