本文選題：五音吐納療法 + 乳腺癌�。� 參考：《廣州中醫(yī)藥大學(xué)》2015年碩士論文

【摘要】：目的：本研究通過(guò)量表評(píng)定的方法,對(duì)臨床數(shù)據(jù)進(jìn)行研究,記錄并評(píng)價(jià)乳癌患者術(shù)后疲勞情況,觀察五音吐納療法改善乳癌術(shù)后疲勞綜合癥的療效,探索五音吐納療法的可行性,為乳癌術(shù)后疲勞綜合癥的中醫(yī)治療探索出一條行之有效的方法,拓寬五音吐納療法的臨床應(yīng)用范圍,加深五音吐納療法和臨床學(xué)科的相融性。方法：收集廣東省第二中醫(yī)院乳腺科2013年5月至2015年1月期間確診為早期乳腺癌的患者共60例,采用區(qū)組隨機(jī)化分組方法分為對(duì)照組和治療組,對(duì)照組予術(shù)后常規(guī)治療,治療組予術(shù)后常規(guī)治療配合五音吐納療法,采用視覺(jué)模擬評(píng)測(cè)表(Visual Analogue Scale, VAS)、簡(jiǎn)明心境量表(Brief Profile of Mood States,BPOMS)及圍手術(shù)期疲勞測(cè)評(píng)量表(Identity-Consequence Fatigue Scale,ICFS)分別在術(shù)前、術(shù)后第1、3、7、14天同一時(shí)間點(diǎn)測(cè)評(píng)并記錄分值,同時(shí)抽血檢測(cè)術(shù)前、術(shù)后第7天白細(xì)胞(white blood cell,WBC)、紅細(xì)胞(red blood cell, RBC)、血紅蛋白(hemoglobin,HGB)、血小板(blood platelet,PLT)、血清總蛋白(serum total protein,STP)、血清白蛋白(serum albumin,ALB)及血清轉(zhuǎn)鐵蛋白(serum transferrin,TF)水平。采用SPSS17.0統(tǒng)計(jì)軟件包,利用EXCEL建立數(shù)據(jù)庫(kù)進(jìn)行數(shù)據(jù)的管理和維護(hù)。統(tǒng)計(jì)方法有卡方檢驗(yàn)、描述性統(tǒng)計(jì)分析方法、正態(tài)檢驗(yàn)及方差齊性分析、兩因素多水平重復(fù)測(cè)量方差分析、多變量方差分析方法、兩樣本秩和比較、兩樣本獨(dú)立t檢驗(yàn)等。結(jié)果：1.符合納入標(biāo)準(zhǔn)的60例病例經(jīng)VAS、BPOMS、ICFS量表評(píng)估,結(jié)果60例乳癌患者術(shù)后均出現(xiàn)不同程度的疲勞,其疲勞分值在不同的時(shí)間點(diǎn)存在差異。2.兩組患者均在術(shù)后第1天的VAS、BPOMS、ICFS量表測(cè)評(píng)中得到較高的疲勞分值,術(shù)后第3天疲勞分值均較術(shù)前第1天下降,并且隨著時(shí)間的推移疲勞分值較前降低。3.治療組與對(duì)照組患者在術(shù)后第1天的VAS、BPOMS、ICFS量表的疲勞分值均處于較高水平,兩組間差異沒(méi)有統(tǒng)計(jì)學(xué)意義(P0.05)。治療組患者術(shù)后第3、7、14天的VAS、BPOMS、CFS量表的疲勞分值比對(duì)照組患者低,差異有統(tǒng)計(jì)學(xué)意義(P0.05)。4.本研究中治療組與對(duì)照組兩組患者分別比較術(shù)前、術(shù)后第7天機(jī)體的WBC、RBC、HGB、PLT、STP及ALB水平,差異無(wú)統(tǒng)計(jì)學(xué)意義(P0.05)。五音吐納療法的干預(yù)不能改變機(jī)體WBC、RBC、HGB、PLT、STP及ALB的水平。結(jié)論：乳癌患者術(shù)后的確存在疲勞情況,其中術(shù)后第1天疲勞程度相對(duì)嚴(yán)重,且從術(shù)后第3天起呈逐漸改善的趨勢(shì)。五音吐納療法對(duì)改善乳癌術(shù)后疲勞綜合癥的效果,主要體現(xiàn)在VAS、BPOMS、ICFS量表的疲勞分值的變化上,但不影響機(jī)體WBC、RBC、HGB、 PLT、STP及ALB水平的變化。五音吐納療法能有效地治療乳癌術(shù)后疲勞綜合癥,具有可行性,值得進(jìn)一步在臨床實(shí)踐中運(yùn)用及推廣。
[Abstract]:Objective: the purpose of this study was to study the clinical data, to record and evaluate the postoperative fatigue of patients with breast cancer, and to observe the curative effect of Wuyongna therapy on the improvement of postoperative fatigue syndrome of breast cancer. In order to explore the feasibility of five-tone toner therapy, explore an effective method for the treatment of postoperative fatigue syndrome of breast cancer, broaden the scope of clinical application of five-tone toner therapy, and deepen the compatibility of five-tone toner therapy and clinical subject. Methods: a total of 60 patients with early breast cancer from May 2013 to January 2015 were collected and randomly divided into two groups: control group and treatment group. The patients in the treatment group were treated with conventional postoperative therapy and five-tone toner therapy. Visual Analogue scale, VASA, brief Profile of Mood status scale (BPO MS) and Identity-Consequence Fatigue scale (ICFSs) were used before operation, respectively. The scores were measured and recorded at the same time point 14 days after operation, and the blood samples were taken before the operation. On the 7th day after operation, the levels of white blood cells, red blood cells, hemoglobin hGBs, platelet platelets, serum total protein, serum albumin (Alb) and serum transferrin (TF) were measured. Using SPSS17.0 statistical software package, using EXCEL to establish database for data management and maintenance. Statistical methods include chi-square test, descriptive statistical analysis method, normal test and homogeneity analysis of variance, two-factor multilevel repeated measurement variance analysis, multivariate variance analysis method, two-sample rank sum comparison, two-sample independent t-test, etc. The result is 1: 1. According to the inclusion criteria, 60 cases were evaluated by VAS-BPOMSMS-ICFS. Results all 60 cases of breast cancer had different degrees of fatigue after operation, and the fatigue scores were different at different time points. On the first day after operation, the fatigue scores of the two groups were higher than those on the first day after operation, and the fatigue scores on the third day after operation were lower than those on the first day before operation, and the fatigue scores decreased by .3with the passage of time. The fatigue scores of the VAS-BPOMSICFS scale in the treatment group and the control group were at a higher level on the first day after operation, and the difference between the two groups was not statistically significant (P 0.05). The fatigue score of VAS-BPOMS CFS scale in the treatment group was lower than that in the control group on the 3rd and 14th day after operation, and the difference was statistically significant (P 0.05). In this study, the STP and ALB levels of the patients in the treatment group and the control group were compared before and 7 days after operation respectively. There was no significant difference in STP and ALB levels between the two groups. The intervention of five tone and intonation therapy could not change the level of ALB and STP. Conclusion: postoperative fatigue does exist in patients with breast cancer, and the fatigue degree is relatively serious on the first day after operation, and gradually improves from the third day after operation. The effect of five-tone toning therapy on the improvement of postoperative fatigue syndrome of breast cancer was mainly reflected in the change of fatigue score of VAS-BPOMS ICFS scale, but it did not affect the changes of the levels of HGB, PLTN STP and ALB in patients with breast cancer. It is feasible to treat postoperative fatigue syndrome of breast cancer with five tones and it is worthy of further application and popularization in clinical practice.
【學(xué)位授予單位】：廣州中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2015
【分類號(hào)】：R737.9

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本文編號(hào)：1946210