本文選題：氯已定 + 聚維酮碘�。� 參考：《四川大學(xué)學(xué)報(bào)(醫(yī)學(xué)版)》2017年03期

【摘要】：目的比較以氯已定和聚維酮碘為主要成分的兩種消毒液進(jìn)行外科消毒降低術(shù)后傷口感染率的效果。方法對(duì)2015年1月至2016年12月在四川大學(xué)華西醫(yī)院施行清潔或可能受污染手術(shù)患者進(jìn)行研究,將納入的335例患者進(jìn)行隨機(jī)分組,試驗(yàn)組160例患者使用質(zhì)量分?jǐn)?shù)2%氯已定進(jìn)行皮膚消毒,對(duì)照組175例患者使用質(zhì)量分?jǐn)?shù)5%聚維酮碘消毒,記錄兩組患者基本臨床資料、術(shù)后30d內(nèi)手術(shù)傷口感染率以及傷口感染部位情況并比較兩組間的差異。結(jié)果共獲得318例患者的完整隨訪數(shù)據(jù),隨訪率為94.9%。其中試驗(yàn)組148例,對(duì)照組170例。兩組患者年齡、性別、術(shù)前及術(shù)后抗生素使用情況、手術(shù)時(shí)間差異均無(wú)統(tǒng)計(jì)學(xué)意義(P0.05)。試驗(yàn)組術(shù)后總感染率低于對(duì)照組(5.4%vs.12.9%,P=0.03)。其中在淺表部位感染方面,試驗(yàn)組優(yōu)勢(shì)較明顯(4.1%vs.10.6%,P=0.03),但深部感染率及器官周?chē)腥韭?兩組間差異無(wú)統(tǒng)計(jì)學(xué)意義(P0.05)。兩種消毒液總感染及淺表部位感染的差異在可能受污染的手術(shù)中有統(tǒng)計(jì)學(xué)意義(P0.05),而在清潔手術(shù)中無(wú)統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論氯已定在預(yù)防可能受污染手術(shù)術(shù)后的總感染及淺表部位感染較聚維酮碘更有優(yōu)勢(shì),但對(duì)于清潔手術(shù),兩種消毒液效果相當(dāng)。
[Abstract]:Objective to compare the effect of surgical disinfection with chlorhexidine and povidone iodine as main components to reduce postoperative wound infection rate.Methods from January 2015 to December 2016, 335 patients undergoing cleaning or potentially contaminated surgery in Huaxi Hospital of Sichuan University were randomly divided into three groups.160 patients in the test group were disinfected with 2% chlorhexidine by mass fraction, 175 patients in the control group were disinfected with 5% povidone iodine by mass fraction. The basic clinical data of the two groups were recorded.The infection rate and site of wound infection within 30 days after operation were compared between the two groups.Results the complete follow-up data of 318 patients were obtained, and the follow-up rate was 94. 9%.There were 148 cases in the test group and 170 cases in the control group.There was no significant difference in age, sex, antibiotic use before and after operation and operation time between the two groups (P 0.05).The total infection rate in the experimental group was lower than that in the control group (5.4 vs 12.9B).In the superficial infection, the advantage of the test group was 4.1vs.10.6, but there was no significant difference between the two groups in the deep infection rate and the infection rate around the organs.The difference of total infection and superficial infection between the two kinds of disinfectant was statistically significant in the potentially contaminated operation (P 0.05), but not in the clean operation (P 0.05).Conclusion chlorine has more advantages in preventing total infection and superficial infection after operation than povidone iodine, but the efficacy of the two disinfectant solutions is the same for cleaning operation.
【作者單位】： 四川大學(xué)華西醫(yī)院麻醉手術(shù)中心;四川大學(xué)華西醫(yī)院泌尿外科;
【分類(lèi)號(hào)】：R614

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