本文選題：咪達(dá)唑侖　切入點(diǎn)：氯胺酮　出處：《中國比較醫(yī)學(xué)雜志》2017年04期 　論文類型：期刊論文

【摘要】：目的比較3種麻醉方法在幼齡小型豬構(gòu)建顱骨缺損模型及修復(fù)實(shí)驗(yàn)中的麻醉效果,從而探索簡便、安全、有效的最佳麻醉方案。方法幼齡貴州小型豬30頭,雌雄各半,隨機(jī)分為3組,每組10頭,A組采用咪達(dá)唑侖與氯胺酮組混合液肌內(nèi)注射;B組采用肌內(nèi)注射陸眠寧Ⅱ注射液麻醉;C組咪達(dá)唑侖聯(lián)合氯胺酮與陸眠寧Ⅱ復(fù)合肌內(nèi)注射麻醉。比較3組的麻醉顯效時(shí)間、首次麻醉維持時(shí)間、第1次追加藥物麻醉維持時(shí)間、第2次追加藥物麻醉維持時(shí)間、蘇醒時(shí)間、術(shù)中麻藥追加次數(shù)、麻藥累積量、術(shù)后動(dòng)物不良反應(yīng)及死亡率。結(jié)果 B組顯效時(shí)間長于A、C兩組(P0.05);C組首次麻醉維持時(shí)間、第1次追加藥物麻醉維持時(shí)間、第2次追加藥物麻醉維持時(shí)間的時(shí)長明顯大于A、B兩組(P0.05);A、C組蘇醒期明顯短于B組(P0.05);C組的追加麻藥的次數(shù)、用藥總劑量、術(shù)后不良反應(yīng)率及死亡率明顯低于A、B組(P0.05)。結(jié)論咪達(dá)唑侖聯(lián)合氯胺酮與陸眠寧Ⅱ復(fù)合麻醉是一種操作簡單、麻醉深度可控、安全性高的適于手術(shù)時(shí)間較長的幼齡小型豬外科實(shí)驗(yàn)的的麻醉方法。
[Abstract]:Objective to compare the anesthetic effects of three kinds of anesthetic methods in establishing skull defect model and repairing experiment in young miniature pigs, so as to explore the simple, safe and effective best anesthetic scheme. Methods 30 young Guizhou miniature pigs, half male and half female, were used in this study. They were randomly divided into three groups. Group A was treated with intramuscular injection of midazolam and ketamine, group B was treated with intramuscular injection of Lumianning 鈪，

本文編號：1581176