發(fā)布時(shí)間：2018-09-17 17:58

【摘要】：高頻剪切波對(duì)粘性參數(shù)的準(zhǔn)確估計(jì)非常重要。為了提高高頻剪切波的檢測(cè)能力,并研究其對(duì)粘彈性參數(shù)估計(jì)的影響,本研究探討了基于正交頻率脈沖激勵(lì)的超聲振動(dòng)計(jì)方法。通過(guò)構(gòu)造具有特定頻譜特性的正交頻率波形,經(jīng)稀疏采樣之后激勵(lì)組織振動(dòng),可以增強(qiáng)剪切波的高頻分量。以新鮮豬肝為對(duì)象進(jìn)行離體實(shí)驗(yàn)。選擇二進(jìn)制編碼和兩種正交頻率編碼脈沖激勵(lì)組織振動(dòng),然后分別運(yùn)用激光振動(dòng)計(jì)和超聲對(duì)不同編碼激勵(lì)方式產(chǎn)生的剪切波進(jìn)行檢測(cè)。激光振動(dòng)計(jì)實(shí)驗(yàn)證明了該方法可以有效增強(qiáng)剪切波的高頻分量,而從超聲實(shí)驗(yàn)結(jié)果上看,與二進(jìn)制編碼激勵(lì)方式的結(jié)果相比,當(dāng)只用100~400 Hz剪切波速度擬合求解時(shí),三碼片與六碼片的正交頻率脈沖激勵(lì)所估計(jì)得到的剪切彈性和剪切粘性的相對(duì)偏差分別為2.3%和4.1%,13.6%和11.5%;而當(dāng)將所有頻率剪切波速度用于擬合求解時(shí),三碼片與六碼片的正交頻率脈沖激勵(lì)所估計(jì)得到的剪切彈性和剪切粘性的相對(duì)偏差分別為10.6%和3.5%,5.4%和11.8%。實(shí)驗(yàn)結(jié)果表明,正交頻率編碼激勵(lì)方式可以降低激勵(lì)峰值聲強(qiáng),并提高系統(tǒng)對(duì)高頻剪切波的檢測(cè)能力;另一方面,高頻剪切波對(duì)粘彈性估計(jì)值具有影響,但其影響方式還不確定,需要進(jìn)一步研究。
[Abstract]:High frequency shear wave is very important for accurate estimation of viscosity parameters. In order to improve the detection ability of high frequency shear wave and to study its influence on the estimation of viscoelastic parameters, an ultrasonic vibrator method based on orthogonal frequency pulse excitation is studied in this paper. The high frequency component of shear wave can be enhanced by constructing the orthogonal frequency waveform with special spectral characteristics, which excites the tissue vibration after sparse sampling. Fresh porcine liver was studied in vitro. Binary code and two orthogonal frequency coded pulses are selected to excite tissue vibration. Then the shearing waves generated by different coded excitation modes are detected by laser vibrometer and ultrasonic respectively. The experiment of laser vibrometer proves that this method can effectively enhance the high frequency component of shear wave. Compared with the results of binary coded excitation method, when the velocity fitting of shear wave is only 100 ~ 400 Hz, the method can be used to solve the problem. The relative deviations of shear elasticity and shear viscosity estimated by the orthogonal frequency pulse excitation of three and six codes are 2.3% and 4.1% 13.6% and 11.5%, respectively, and when all frequency shear wave velocities are used to fit the solution, the relative deviations of shear elasticity and shear viscosity are 2.3% and 4.1% and 11.5% respectively, and when all frequency shear wave velocities are used to fit the solution, The relative deviations of shear elasticity and shear viscosity obtained by the orthogonal frequency pulse excitation of three and six codes are 10.6% and 3.5% respectively. The experimental results show that the orthogonal frequency coded excitation method can reduce the peak sound intensity and improve the detection ability of the system to the high frequency shear wave, on the other hand, the high frequency shear wave has an effect on the viscoelastic estimation. But its influence mode is still uncertain, need further research.
【作者單位】： 浙江大學(xué)生物醫(yī)學(xué)工程與儀器科學(xué)學(xué)院;電子與計(jì)算機(jī)工程系 圣克勞德州立大學(xué);深圳大學(xué)醫(yī)學(xué)院生物醫(yī)學(xué)工程系;醫(yī)學(xué)超聲國(guó)家聯(lián)合地方工程實(shí)驗(yàn)室;深圳大學(xué)醫(yī)學(xué)院廣東省生物醫(yī)學(xué)信息檢測(cè)與超聲成像重點(diǎn)實(shí)驗(yàn)室;
【分類(lèi)號(hào)】：R310

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