中國漢族特應(yīng)性皮炎4757例患者過敏史相關(guān)性分析
發(fā)布時間:2019-08-12 17:43
【摘要】:目的探討中國漢族特應(yīng)性皮炎(AD)患者同時患有過敏性鼻炎(allergic rhinitis,AR)、哮喘(asthma,AS)等疾病時對AD表型的影響。方法利用2001年11月-2010年5月收集的4 757例AD患者資料,采用SPSS20.0軟件進行卡方檢驗,分析不同過敏史對AD表型的影響。結(jié)果 1AD同時患有AR與南方地區(qū)(P=1.51×10~(-18))正相關(guān),與伴發(fā)耳廓下裂隙(P=1.75×10~(-7))負(fù)相關(guān),與其他表型無關(guān);2AD同時患有AS與南方地區(qū)(P=4.39×10~(-20))、掌紋癥(P=5.06×10~(-9))、眶周黑暈(P=3.10×10~(-7))正相關(guān),與伴發(fā)干皮癥(P=2.13×10~(-6))、早年發(fā)病(P=1.35×10~(-3))、耳廓下裂隙(P=1.35×10~(-4))負(fù)相關(guān),與其他表型無關(guān);3AD同時患有AR+AS與南方地區(qū)(P=2.76×10~(-13))、伴發(fā)掌紋癥(P=1.70×10~(-5))、眶周黑暈(P=2.42×10~(-5))正相關(guān),與其他表型無關(guān);4AD伴過敏家族史與毛周角化癥(P=1.46×10~(-3))、耳廓下裂隙(P=3.34×10~(-5))正相關(guān),與南方地區(qū)(P=4.63×10~(-32))負(fù)相關(guān),與其他表型無關(guān)。結(jié)論 AD伴發(fā)不同過敏史與不同地域有關(guān),同時影響伴發(fā)癥狀的發(fā)生。
[Abstract]:Objective to investigate the effect of allergic rhinitis (allergic rhinitis,AR) and asthma (asthma,AS) on AD phenotype in Chinese Han patients with atopic dermatitis (AD). Methods the data of 4757 patients with AD collected from November 2001 to May 2010 were analyzed by chi-square test with SPSS20.0 software. The effects of different allergic history on AD phenotype were analyzed. Results AR was positively correlated with AR in southern China (P 鈮,
本文編號:2525865
[Abstract]:Objective to investigate the effect of allergic rhinitis (allergic rhinitis,AR) and asthma (asthma,AS) on AD phenotype in Chinese Han patients with atopic dermatitis (AD). Methods the data of 4757 patients with AD collected from November 2001 to May 2010 were analyzed by chi-square test with SPSS20.0 software. The effects of different allergic history on AD phenotype were analyzed. Results AR was positively correlated with AR in southern China (P 鈮,
本文編號:2525865
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